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Tag: Cancer: Breast

A combination of breast conservation surgery and radiation is as effective as breast removal for some women with large

Not All Large Breast Tumors Warrant Mastectomy

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Findings suggest doctors shouldn't automatically rule out less invasive surgery plus radiation
There were substantial shifts in treatment patterns for ductal carcinoma in situ from 1991 to 2010

Treatment Patterns for DCIS Shift From 1991 to 2010

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Highest proportion of patients opts for lumpectomy and radiation therapy
Women in certain racial/ethnic groups are more likely to be diagnosed with more advanced breast cancer

Advanced-Stage Breast CA More Likely in Certain Racial Groups

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African-American, white Hispanic women more likely to receive non-guideline-concordant treatment
Even with recent strides in breast cancer treatment

Early Detection Still Key to Breast Cancer Survival

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Despite advances in treatment, finding smaller tumors linked to better results
Only about one-third of women receive genetic counseling before they undergo testing for BRCA mutations

Too Few Women Getting Counseling Before BRCA Test

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But outside expert questions whether counseling may be more important after a positive test result
A 21-gene risk of recurrence score can identify patients with breast cancer who may be spared chemotherapy

Prospective Validation of 21-Gene Risk of Recurrence Score

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Score identifies breast cancer patients with low risk of recurrence who may be spared adjuvant chemo
Greater numbers of high-risk women eligible for primary prevention of breast cancer are identified by incorporating benign breast disease diagnoses into the Breast Cancer Surveillance Consortium risk model

Adding Benign Breast Dz to Risk Model May Boost Preventive Care

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Found to increase the number of high-risk women deemed eligible for primary prevention
From 2003 to 2102 there was a significant increase in preoperative breast magnetic resonance imaging use in women with breast cancer

Preoperative Breast MRI Use Increased From 2003 to 2012

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Eight-fold increase during 10-year period; MRI use linked to more ancillary investigations
The risks of developing an ipsilateral breast event and an invasive IBE increased over time for patients with ductal carcinoma in situ who were selected on the basis of favorable clinical and pathologic characteristics for surgical excision without radiation

Ipsilateral Breast Event Risk Higher Over Time With DCIS

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Findings in patients with surgery, no radiation based on favorable clinical factors
A Mediterranean diet supplemented with extra-virgin olive oil may reduce the risk of breast cancer

Mediterranean Diet With Olive Oil Cuts Breast Cancer Risk

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Beneficial effect of Mediterranean diet plus extra-virgin olive oil in primary prevention