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Tag: Cancer: Breast

Free flap breast reconstruction is a viable and safe procedure in elderly patients

Free Flap Breast Reconstruction Safe in Elderly Patients

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Older women want breast reconstruction at rates similar to those of nonelderly breast cancer patients
Digital mammography has increased the overall cancer detection rate by 14 percent

Breast CA Detection Rate Up With Digital Mammography in the U.K.

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Rate of detection increased 14 percent; detection rates higher for grade 1, 2 invasive cancers
The increased risk for breast cancer that occurs after childbirth can last more than 20 years

Higher Risk for Breast Cancer After Childbirth May Last 20+ Years

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Risk peaks five years after childbirth but continues until 24 years postbirth
Women who have participated in mammography screening have a lower risk for dying from breast cancer within 10 and 20 years after diagnosis

Breast Screening Linked to Lower Risk for Breast Cancer Death

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Screening linked to 60 percent lower risk for dying from breast cancer within 10 years after diagnosis
Tamoxifen at a dose of 5 mg/day is associated with a reduced risk for recurrence for women with hormone-sensitive breast intraepithelial neoplasia

SABCS: Low-Dose Tamoxifen Cuts Risk for Breast Dz

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More second primary cancers and more frequent menopausal symptoms seen in tamoxifen vs. placebo arm
Black women with breast cancer have worse clinical outcomes even when 21-gene recurrence scores are similar

SABCS: Breast Cancer Outcomes Worse for Blacks Despite Similar Gene RS

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Black race was associated with worse clinical outcomes among entire population
Subsequent imaging is required for 10 to 15.5 percent of women who undergo mastectomy

Imaging, Biopsy Often Still Needed After Mastectomy

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10 to 15.5 percent of women undergo subsequent imaging; 6 to 8 percent undergo biopsy
For patients with residual invasive disease after neoadjuvant chemotherapy including a taxane and trastuzumab

SABCS: T-DM1 Cuts Recurrent Invasive HER2+ Breast CA Risk

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Risk reduced with trastuzumab emtansine in those with residual invasive dz at sx after neoadjuvant chemo
Delaying initiation of adjuvant chemotherapy in triple-negative breast cancer patients more than 30 days after surgery is associated with a decrease in survival

SABCS: Delaying Chemo Lowers Survival in Triple-Neg Breast CA

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Findings show delaying chemo over 30 days postsurgery lowers triple-negative breast cancer survival
Though common breast cancer variants indicate increased breast cancer risk

Rare Variants Associated With Interval Breast Cancers

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The presence of these variants is also linked to increased risk for death