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Tag: Cancer: Breast

An antibody-drug conjugate

Sacituzumab Govitecan Promising in Triple-Negative Breast Cancer

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Response rate of 33.3 percent, median response duration of 7.7 months observed in 108 patients
The multigene expression test Oncotype DX is not cost-effective for women with breast cancer who are at low risk for recurrence

Oncotype DX Not Cost-Effective for Low-Risk Breast Cancer

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Incremental cost-effectiveness ratio varies across clinical risk groups, sensitive to patient age
The U.S. Preventive Services Task Force (USPSTF) recommends screening for women at increased risk for carrying a BRCA1/2 mutation as well as genetic counseling and testing as indicated for those screening positive. These recommendations form the basis of a draft recommendation statement published online Feb. 19 by the USPSTF.

USPSTF Says Screen Women With Higher Risk for BRCA Mutations

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Those with positive results should be provided with genetic counseling, testing if indicated
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p, p’-DDT Exposure Linked to Breast Cancer Through Age 54

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Risk for breast cancer varies based on timing of first exposure, age at diagnosis
From 1989 to 2018

More Than a Half Million Deaths From Breast Cancer Averted

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Percent of breast cancer mortality reductions varied from 45.3 to 58.3 percent from 1989 to 2018
Autologous breast reconstruction after failed implant-based reconstruction seems safe and is associated with improved patient outcomes

Outcomes Good for Autologous Reconstruction After Implant Fail

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Autologous breast reconstruction associated with improved patient satisfaction, quality of life
Recommendations have been developed to improve accuracy

Use of Image Analysis to ID HER2 Status in Breast Cancer Outlined

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Guideline addresses use of quantitative image analysis to interpret HER2 immunohistochemistry
Women with breast cancer have an increased long-term incidence of atrial fibrillation

Long-Term Incidence of A-Fib Increased in Women With Breast Cancer

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Women younger than 60 years have increased short-term, longer-term risk
The time to surgery after a breast cancer diagnosis is delayed for non-Hispanic black versus non-Hispanic white women

Time to Breast Cancer Surgery Delayed for Non-Hispanic Blacks

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Racial differences in TTS did not explain racial differences in overall survival with breast-conserving sx
Among breast cancer patients

Breast Cancer Patients Do Not Overreact to Genetic Testing

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No increased cancer worry for multigene panel testing versus BRCA1/2-only test after cancer diagnosis