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Tag: Cancer: Breast

The incidence of breast cancer for women aged 25 to 39 years has been increasing since 1935 and seems not to be related to changes in parity over time

Breast Cancer Incidence Rising for Young Women Since 1935

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Increase began before secular decrease in parity and cannot be attributed to changes in parity over time
Abbreviated magnetic resonance imaging is associated with a significantly higher rate of invasive breast cancer detection compared with digital breast tomosynthesis among women with dense breasts

Invasive Breast Cancer Detection Up With Abbreviated Breast MRI

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Detection rate for invasive breast cancer significantly higher with MRI versus digital breast tomosynthesis
Higher intakes of dairy milk are associated with a greater risk for breast cancer

Dairy Milk Tied to Higher Breast Cancer Risk

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Findings similar regardless of full-fat or reduced-fat milk consumption
In a cohort of unselected postmenopausal women with breast cancer

Genetic Mutations ID’d in Breast Cancer After Menopause

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3.55 percent of unselected postmenopausal women with breast cancer have pathogenic variants
Expansion of National Comprehensive Cancer Network hereditary cancer testing criteria to include all women diagnosed with breast cancer at ≤65 years would improve the sensitivity of detection of germline pathogenic variants

Genetic Testing Proposed for All Women ≤65 With Breast Cancer

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Expanded testing could increase detection of carriers for BRCA1/2, mutations in other predisposition genes
Almost half of young women with a breast cancer diagnosis experience financial decline

Many Young Women With Breast Cancer Experience Financial Decline

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Common concerns among employed respondents include increased time off, suffering job performance
Use of acid reflux drugs (proton pump inhibitors) during and after cancer treatment may be tied to impaired memory and concentration in breast cancer survivors

Use of PPIs Tied to Cognitive Issues in Breast Cancer Survivors

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Concentration, memory problems reported in breast cancer patients at different stages of survivorship
Many women with early-stage breast cancer who test positive for an inherited genetic variant are receiving cancer treatment that does not follow current guidelines

Treatment for Hereditary Breast Cancer Not Always Guideline-Concordant

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Treatment seems less in line with practice guidelines, particularly for radiation therapy and chemotherapy
For patients with untreated stage II or III triple-negative breast cancer

Adding Pembrolizumab May Up Response in Triple-Negative Breast Cancer

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Pathological complete response rate higher with pembrolizumab plus neoadjuvant chemotherapy
For women aged 75 years or older

Continuing Annual Breast Cancer Screening No Benefit in Over-75s

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No significant reductions found in eight-year breast cancer mortality for continuing versus stopping screening