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Tag: Cancer: Breast

SABCS: Imlunestrant Tied to Improved PFS for ER-Positive, HER2-Negative Breast Cancer With ESR1 Mutations

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Imlunestrant leads to significantly longer progression-free survival among those with ESR1 mutations, but not in overall population

2004 to 2021 Saw Increase in Distant-Stage Breast Cancer Incidence

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Significant increase seen in incidence rates at presentation for women overall, and for those aged 20 to 39, 40 to 74, and 75 years or older

Low-Dose Oral Minoxidil Effective for Alopecia in Breast Cancer

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All patients receiving surgery/radiotherapy alone or with chemotherapy had improvement or stability of alopecia with LDOM

Adding Previous Screening Mammogram Images Improves Cancer Prediction

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Five-year AUC with addition of previous mammogram images improves current visit mammogram AUC

Neoantigen DNA Vaccines Safe, Induce Response in Triple-Negative Breast Cancer

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Fourteen of 18 patients had neoantigen-specific T-cell responses; recurrence-free survival was 87.5 percent at 36 months

Inavolisib + Palbociclib-Fulvestrant Improves Survival in Advanced Breast Cancer

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Inavolisib leads to significantly longer progression-free survival, with no increase seen in incidence of toxic events

Multigene Signature Can Help Tailor Chemo for Operable Triple-Negative Breast Cancer

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Improved three-year disease-free and recurrence-free survival seen with intensive chemotherapy regimen

Guideline-Concordant Care Less Likely With Non-Hispanic Black Race

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Findings seen in older patients with breast cancer; non-Hispanic Black patients also less likely to have timely initiation of treatment

Medicaid Expansion Increases Guideline-Concordant Treatment for Breast Cancer

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Increase seen in receipt of guideline-concordant treatment for women newly diagnosed with HR-negative, HER2-positive breast cancer

No Objective Improvement Seen in Cognitive Function With Exercise During Chemo

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Significant differences seen in four of six self-reported cognitive function outcomes favoring aerobic exercise initiated with chemo