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Tag: Cancer: Bladder

Childhood body mass index is positively associated

High BMI in Childhood May Up Risk for Bladder Cancer as Adult

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Height inversely linked to bladder cancer, while excess BMI gain in childhood linked to increased risk
For patients with metastatic urothelial carcinoma

Addition of Atezolizumab May Aid in Metastatic Urothelial Cancer

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Phase 3 trial shows prolonged progression-free survival for atezolizumab plus platinum-based chemo
The June 2018 U.S. Food and Drug Administration label restriction on first-line immunotherapy for advanced bladder cancer was associated with a decrease in immunotherapy use and an increase in chemotherapy use

FDA Labeling Restriction Quickly Reflected in Oncology Practice

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FDA label change linked to decrease in immunotherapy use, increases in chemotherapy use, PD-L1 testing
Among postmenopausal women

Quitting Smoking Lowers Risk for Bladder Cancer Postmenopause

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Significant drop seen in first 10 years of cessation, continues to decrease as cessation time increases

American Urological Association, May 3-6

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The American Urological Association 2019 Annual Meeting The annual meeting of the American Urological Association was held from May 3 to 6 in...
The first personalized treatment for patients with metastatic bladder cancer and susceptible fibroblast growth factor receptor genetic alterations was granted accelerated approval by the U.S. Food and Drug Administration

FDA Approves Personalized Tx for Metastatic Bladder Cancer

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Balversa indicated for treatment of bladder cancer with FGFR3 or FGFR2 genetic alteration
An earlier age at menopause is associated with a higher risk for bladder cancer

Younger Age at Menopause Tied to Higher Risk for Bladder Cancer

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Women with menopause onset by age 45 at higher risk than those with onset at age 50 or older
Cigarette smoking is linked to a poor response to cisplatin-based neoadjuvant chemotherapy among patients with muscle-invasive bladder cancer who undergo radical cystectomy

Smoking Associated With Worse Bladder Cancer Outcomes

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Smokers had poorer response to cisplatin-based neoadjuvant chemotherapy, higher recurrence risk
Noninvasive diagnostic imaging using machine-learning analysis of nanoresolution images of cell surfaces can detect bladder cancer with high diagnostic accuracy

Noninvasive Diagnostic Imaging Accurately IDs Bladder Cancer

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Method evaluating cells collected from urine shows 94 percent diagnostic accuracy
Cancer treatment is associated with a clinically meaningful survival benefit in older

Treatment Tied to Survival Benefit in Complex Bladder Cancer

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Medically complex patients with superficial disease have reduced deaths with treatment vs. observation