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Gene Therapy for Sickle Cell Did Not Cause Patient’s Leukemia

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Bluebird Bio says it has not found evidence that its gene therapy caused the sickle cell patient's leukemia

Whole-Genome Sequencing Is Accurate for Myeloid Cancers

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Prospective sequencing of samples provided new genetic information for 24.8 percent of patients, which changed risk category for 16.2 percent

Erythrocytosis ID’d in 11 Percent of Trans Men Using Testosterone

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Factors associated with erythrocytosis include tobacco use, long-acting undecanoate injections, age at initiation of testosterone

Lipid Screen

Blood Lead Level Testing Among Children Decreased During COVID-19

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Estimated 9,603 children with elevated BLL were missed due to decreased testing in January to May 2020

ASH

Groups Jointly Issue Guidelines for Von Willebrand Disease

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ASH, ISTH, NHF, and WFH developed clinical guidelines for the diagnosis, management of von Willebrand disease

Preoperative Blood Transfusion Not Beneficial for Surgery in Neonates

Higher Hb Threshold for Transfusion Not Better for Preemies

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Use of a higher hemoglobin threshold for transfusion in anemic preterm infants does not lower risk for death, neurodevelopmental impairment

B 12/21 -- Certain Cancer Patients at Higher Odds for Severe COVID-19

Secondary Bloodstream Infections Tied to Poorer COVID-19 Outcomes

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Altered mental status, ICU admission, higher in-hospital mortality more likely in hospitalized patients with severe COVID-19 and sBSI

HealthDay Reports: Blood Type
Broader Genetic Testing Could ID More Heritable Cancers

ASH: CRISPR-Cas9 Gene Editing Promising in TDT, SCD

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Total hemoglobin, fetal Hb increased in seven patients with transfusion-dependent ß-thalassemia, three with sickle cell disease

Broader Genetic Testing Could ID More Heritable Cancers

ASH: CRISPR-Cas9 Gene Editing Promising in TDT, SCD

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Total hemoglobin, fetal Hb increased in five patients with transfusion-dependent ß-thalassemia, two with sickle cell disease