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New definitions and criteria for sepsis and septic shock have been published online Feb. 22 in the Journal of the American Medical Association to coincide with the Society of Critical Care Medicine's 45th Critical Care Congress

SCCM: New Definitions, Criteria Developed for Sepsis

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New criteria identify adult patients likely to have poor outcomes typical of sepsis
Most patients with thrombocytopenia have circulating histones

SCCM: Circulating Histones for Most With Thrombocytopenia

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Circulating histones for 91 percent of patients with thrombocytopenia, 55 percent of controls
A new T-cell immunotherapy has led to sustained regression in many previously relapsing and treatment-resistant cases of acute lymphoblastic leukemia

New Immune Tx Achieves Remission in B-Cell Malignancies

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Patient's T cells are engineered with chimeric antigen receptors
Activated factor VII-antithrombin complex levels correlate with increased mortality risk in patients with coronary artery disease

Factor VII-Antithrombin Complex Predicts Mortality in CAD

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Patients with FVIIa-AT levels above median at baseline have two-fold increased mortality
Caplacizumab

Caplacizumab Shows Potential for Treating Acquired TTP

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In a phase 2 study, the biopharmaceutical induced faster resolution of acute TTP episode than placebo
A new microchip-flow chamber system can be used to discriminate and predict bleeding score in type 1 von Willebrand disease

New System Can Assess Severity of Von Willebrand Disease

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Microchip-flow chamber system can discriminate and predict the bleeding score in type 1 VWD
The American Red Cross on Wednesday asked potential blood donors who have traveled to areas where Zika infection is active to wait 28 days before giving blood.

Blood Donors at Risk for Zika Infection Asked to Hold Off

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American Red Cross asks potential donors who have traveled to affected areas to wait 28 days
The incidence of primary chronic immune thrombocytopenia (cITP) is 2.30/100

Infection Risk Up Before Chronic Immune Thrombocytopenia

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Increased risk of infections requiring inpatient, outpatient care within five years before cITP dx
For warfarin-treated patients

Carbamazepine Affects Warfarin Anticoagulation

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Carbamazepine co-treatment linked to subtherapeutic anticoagulative effect of warfarin
For patients with nonvalvular atrial fibrillation

Review: Dabigatran Comparable to Warfarin for Nonvalvular A-Fib

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Linked to lower risk of intracranial bleeding, but higher risk of gastrointestinal bleeding