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A cluster of rare bloodstream infections was discovered by Illinois health officials while investigating an outbreak in Wisconsin.

Ten Cases of Rare Bloodstream Infection Reported in Illinois

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Cases of infection from the bacterium Elizabethkingia included six deaths
Implantation of sliding growth guidance instrumentation LSZ-4D

Metal Up in Blood With Titanium Growth Guidance Sliding Device

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Increased content of metal ion in blood and tissue around implanted device in children with scoliosis
Recommendations have been issued for the use of direct oral anticoagulants in obese patients; the guideline was published online March 22 in the Journal of Thrombosis and Haemostasis.

Guidance Issued on Use of Direct Oral Anticoagulants in Obese

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DOAC use not recommended for patients with BMI >40 kg/m² and weight >120 kg
There is considerable variation in estimates of sepsis mortality using death certificates and health services utilization data (administrative claims)

Variation in Estimates of Sepsis-Linked Mortality by Data Source

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Variation seen comparing mortality based on deaths certificates and health services utilization data
Extended-release niacin is associated with progressive and reversible thrombocytopenia

Niacin-ER May Be Overlooked Cause of Thrombocytopenia

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Researchers also note marked improvement in hemoglobin upon drug discontinuation in anemia
An experimental test to check blood donations for the Zika virus has been approved by the U.S. Food and Drug Administration.

FDA Allows Use of Investigational Zika Test for Blood Donations

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But agency still asks those who've possibly been exposed to the virus to forgo giving blood right now
A slightly lower serum sodium concentration within the normal range is a major risk factor for mortality in elderly adults

Low-Normal Sodium Deemed Major Risk for Mortality in Elderly

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Sodium level corrected according to serum glucose concentration, a better measure
Switching from prasugrel to ticagrelor is associated with a transient increase in platelet inhibition

ACC: Higher Platelet Inhibition With Switch to Ticagrelor

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Switching from prasugrel to ticagrelor linked to transiently increased levels of platelet inhibition
A rare case of immobility-induced hypercalcemia in an infant has been documented in a case report published online March 18 in Pediatrics.

Case Report: Immobility-Induced Hypercalcemia in Infant

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Infant presented with fatigue, irritability, failure to gain weight after prolonged immobilization
Patients with diabetes may be significantly more likely to develop community-acquired Staphylococcus aureus bacteremia than those without diabetes

Diabetes Patients More Susceptible to Staph Bacteremia

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Risk up seven-fold among patients with type 1 diabetes, almost three-fold for those with type 2