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The experimental drug midostaurin may reverse organ damage in patients with advanced systemic mastocytosis

Midostaurin Beneficial in Advanced Systemic Mastocytosis

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Organ damage improved in 60 percent of patients with advanced systemic mastocytosis
The Zika virus is spreading through Puerto Rico

CDC: New Test May Help Screen Blood Donations for Zika

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Researchers using investigational nucleic acid test to screen blood for Zika
Patients taking systemic glucocorticoids are at higher risk for community-acquired Staphylococcus aureus bacteremia

Risk of S. aureus Bacteremia Up in Patients on Glucocorticoids

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Community-acquired Staphylococcus aureus bacteremia risk rose along with the dosage
Daratumumab (Darzalex)

ASCO: Adding Daratumumab Early in Myeloma Treatment Efficacious

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Response rate doubled for patients with relapsed or refractory multiple myeloma
For patients with relapsed

Ixazomib Ups Progression-Free Survival in Multiple Myeloma

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Up in all prespecified patient groups, including those with high-risk cytogenetic abnormalities
The incidence of transfusion-transmitted malaria can be reduced with use of a whole blood pathogen-reduction system

Pathogen Reduction System Prevents Malaria Via Transfusion

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Plasmodium inactivation in whole blood reduces incidence of transfusion-transmitted malaria
A cluster of rare bloodstream infections was discovered by Illinois health officials while investigating an outbreak in Wisconsin.

Ten Cases of Rare Bloodstream Infection Reported in Illinois

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Cases of infection from the bacterium Elizabethkingia included six deaths
Implantation of sliding growth guidance instrumentation LSZ-4D

Metal Up in Blood With Titanium Growth Guidance Sliding Device

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Increased content of metal ion in blood and tissue around implanted device in children with scoliosis
Recommendations have been issued for the use of direct oral anticoagulants in obese patients; the guideline was published online March 22 in the Journal of Thrombosis and Haemostasis.

Guidance Issued on Use of Direct Oral Anticoagulants in Obese

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DOAC use not recommended for patients with BMI >40 kg/m² and weight >120 kg
There is considerable variation in estimates of sepsis mortality using death certificates and health services utilization data (administrative claims)

Variation in Estimates of Sepsis-Linked Mortality by Data Source

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Variation seen comparing mortality based on deaths certificates and health services utilization data