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Using the freshest blood for transfusions does not appear to significantly improve patient survival

Survival Outcomes Similar for Short-, Long-Term Blood Storage

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No significant difference seen in patient survival rates
In a clinical practice guideline published online Oct. 12 in the Journal of the American Medical Association

New Recs for RBC Transfusion, Optimal RBC Storage Length

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Restrictive red blood cell transfusion threshold of 7 g/dL recommended for most hospitalized adults
For adults with sepsis

Levosimendan Doesn’t Prevent Acute Organ Dysfunction

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Drug also tied to lower odds of successful weaning from mechanical ventilation in adults with sepsis
Empirical treatment with micafungin seems not to increase invasive fungal infection-free survival at 28 days for patients with intensive care unit-acquired sepsis with Candida colonization

Empirical Micafungin Treatment Doesn’t Improve Survival

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No increase in invasive fungal infection-free survival for ICU-acquired sepsis, Candida colonization
The use of hydrocortisone does not reduce the risk of septic shock within 14 days among adults with severe sepsis not in septic shock

Hydrocortisone Doesn’t Cut Risk of Septic Shock in Sepsis

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Among adults with severe sepsis not in septic shock, no reduction in septic shock with hydrocortisone
In obese patients

Changes in Blood Microbiota in Obese With Liver Fibrosis

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Among obese patients, 16S rDNA concentration significantly higher for those with liver fibrosis
Fatal anaphylaxis cases have been reported with administration of intravenous iron products

Reports of Fatal Anaphylaxis With IV Iron Products

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Seventy-nine cases of anaphylactic reactions linked to ferumoxytol, of which 18 were fatal
A simple saline-based nasal spray is as effective as medicated sprays in controlling epistaxis in patients with hereditary hemorrhagic telangiectasia

Saline-Based Nasal Spray Found to Be Effective for Epistaxis

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Saline as good as medications for hereditary hemorrhagic telangiectasia, researchers find
For patients with new-onset diabetic ketoacidosis and severe hyperglycemia

Metformin, Sitagliptin Prolong Normoglycemia Remission in DKA

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Findings in African-American patients with new-onset diabetic ketoacidosis and severe hyperglycemia
Thrombocytopenia is common in pregnancy and can have causes that are serious medical disorders

ACOG Addresses Thrombocytopenia in Pregnancy

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Thrombocytopenia is common; some causes could have potential for maternal, fetal morbidity