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For patients with sepsis requiring mechanical ventilation

DEX Doesn’t Reduce Mortality in Those With Sepsis on Ventilator

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Dexmedetomidine also did not reduce ventilator-free days for sepsis patients on mechanical ventilation
Acetylsalicylic acid hyporesponsiveness after coronary artery bypass graft surgery can be overcome by multiple dosing

Multiple Dosing Mitigates ASA Hyporesponsiveness After CABG

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Multiple dosing more effective than ASA 81 or 325 mg once-daily for suppressing serum TXB2 formation
For patients with septic shock in U.S. hospitals affected by a 2011 norepinephrine shortage

2011 Norepinephrine Shortage Upped Mortality in Septic Shock

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Patients with septic shock in hospitals affected by drug shortage had increased rate of in-hospital death
For patients with locally-advanced non-small-cell lung cancer

Raised CTCs Precede Recurrence in Locally-Advanced NSCLC

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Fifteen of 20 patients with recurrence had increase in circulating tumor cell counts post chemoradiation
For patients with hereditary angioedema with C1 inhibitor deficiency

Lanadelumab Active in Angioedema With C1 Inhibitor Deficiency

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Reduced cleavage of high-molecular-weight kininogen and reduction in attacks of angioedema
A patient-reported symptom score can help predict clinical outcomes in patients with light-chain amyloidosis

Patient-Reported Symptom Score Predicts Outcome in Amyloidosis

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Patient-reported fatigue is independent prognostic factor for survival in light-chain amyloidosis
Considerable variation is seen in risk assessment for newborn early onset sepsis

Evaluation of Sepsis Varies Across Newborn Nurseries

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Obstetric diagnosis of chorioamnionitis is most commonly used factor to identify risk for EOS
Measuring blood neurofilament light chain levels may help distinguish Parkinson's disease from atypical parkinsonian disorders

Diagnostic Potential for Blood-Based NfL in Parkinson’s Disease

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Blood neurofilament light chain levels may prove useful in both primary care and specialized clinics
Significant differences are seen for immunochemical

Significant Differences for Methods of Measuring Albumin

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Biases for plasma samples generally higher than for serum samples for all measurement methods
Hypoglycemia can promote mobilization of specific subsets of leukocytes and induce pro-inflammatory functional changes in immune cells

Hypoglycemia Induces Pro-Inflammatory Functional Changes

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Increases numbers of leukocytes in healthy controls, patients with normal awareness of hypoglycemia