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Home Tags Birth Defects: Misc.

Tag: Birth Defects: Misc.

The American College of Obstetricians and Gynecologists has issued a statement and practice advisory in support of new guidelines aimed at shielding pregnant women from the mosquito-borne Zika virus.

ACOG Supports CDC’s Zika Virus Travel Precautions

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Travel to affected regions not recommended for pregnant women or women considering pregnancy
U.S. health officials issued guidelines Tuesday for health care providers whose pregnant patients may have traveled to countries -- especially Brazil -- where the mosquito-borne Zika virus has been linked to microcephaly.

CDC Issues Zika-Virus Guidance for Health Care Providers

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Ask about recent travel to high-risk areas and symptoms such as sudden fever
Gestational exposure to paroxetine in the first trimester is associated with increased risk of major congenital malformations and major cardiac malformations

Review: Paroxetine Use in Pregnancy Tied to Malformations

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Increased risk of any major congenital malformations, major cardiac malformations
Exposure to oral contraception in early pregnancy does not appear to increase the risk of birth defects

Exposure to Oral Contraceptives Not Tied to Birth Defects

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Findings should reassure women and their doctors, researchers say
Preeclampsia may increase risk of congenital heart defects

Preeclampsia Tied to Congenital Heart Defects

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But researchers stress the risk is still very low
Cerebral palsy is likely due to multiple prenatal factors

Birth Asphyxia Tied to Fewer Than 10% of Cerebral Palsy Cases

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Review suggests that causes other than asphyxia account for most cases in infants born at, near term
Women who follow a very healthy diet are much less likely than those who eat poorly to have a baby with tetralogy of Fallot or atrial septal defects

Healthier Diet Linked to Reduced Congenital Heart Defects

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Tied to reduced risks of tetralogy of Fallot and atrial septal defects
New research provides more evidence of a possible link between selective serotonin reuptake inhibitor antidepressant use early in pregnancy and a small increased risk of birth defects. The study appears online July 8 in The BMJ.

Another Study Shows Link Between SSRIs and Birth Defects

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But finding doesn't prove medications caused increased risk of birth defects
Curcumin appears to reduce high glucose-induced neural tube defect formation by blocking cellular stress and activation of caspases

Curcumin Reduces High Glucose-Induced NTDs in Mice Embryos

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Suppresses oxidative stress, blocks endoplasmic reticulum stress, abolishes caspase 3 and 8 cleavage
Evidence-based folate concentration guidelines for the prevention of neural tube defects have been developed by the World Health Organization

WHO Offers Evidence-Based Folate Concentration Guidelines

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For greatest decrease in neural tube defects, RBC folate concentrations should be >400 ng/mL