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Tag: Asthma

For patients with uncontrolled asthma despite treatment with long-acting beta-agonists and medium-to-high doses of inhaled glucocorticoids

Reduced Asthma Exacerbations Seen With Tezepelumab

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Reduction seen with three dose levels of tezepelumab regardless of blood eosinophil counts
Asthma is associated with subsequent development of inflammatory bowel disease

Asthma Tied to Later Inflammatory Bowel Disease

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Findings for Crohn's and early- or late-onset ulcerative colitis
In 2015

Global Disease Burden of COPD, Asthma Quantified

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More deaths due to COPD than asthma worldwide in 2015; increase in COPD deaths since 1990
Probiotic administration during the first six months of life does not reduce the incidence of eczema at 2 years of age or asthma at 5 years of age

Probiotics in Infancy Do Not Reduce Incidence of Eczema

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Probiotics in first six months of life do not reduce incidence of eczema at age 2, asthma at age 5
Maternal exposure to diesel exhaust particles during pregnancy may increase susceptibility to allergic asthma in more than one generation of offspring

Pollutant Exposure May Lead to Multi-Generational Asthma Risk

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Elevated susceptibility to allergic asthma persists into F2, and with lesser magnitude, into F3 mice
Children whose mothers have uncontrolled asthma during pregnancy are at increased risk of developing the disease at a young age

Maternal Uncontrolled Asthma Ups Risk of Asthma in Offspring

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Association seen for early-onset persistent and transient asthma in children
There is a causal relationship between increasing body mass index and asthma and decreased lung function

Increasing BMI Causally Linked to Asthma, Not Hay Fever

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Significant correlation for genetic risk score with FEV1, FVC per BMI-increasing allele
For patients with infections

Protective Association Identified for Asthma Against Sepsis

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Decreased risk for hospital mortality, septicemia, sepsis, severe sepsis, and septic shock
Climate change may increase people's exposure to an outdoor fungus that can damage airway cells

Global Climate Change Could Cause Rise in Airway Irritation

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Researchers warn about possible increase of Alternaria alternata fungus
Administration of allergen immunotherapy in patients with allergic asthma leads to lower short-term symptom and medication scores

Short-Term Benefits for Immunotherapy in Allergic Asthma

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Reductions seen in short-term symptom scores and medication scores, with evidence of publication bias