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Aspirin may not be effective for primary prevention of cardiovascular disease and cancer mortality

Aspirin May No Longer Have Effect in Primary CVD Prevention

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Also no significant decrease seen in cancer death in studies from 2005 onward
Evidence supports the use of high-dose aspirin for treating acute migraine and low-dose aspirin for prevention of recurrent attacks

Evidence Supports Use of High-Dose Aspirin for Migraine

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High-dose aspirin safe, effective for acute migraine; low-dose aspirin can prevent recurrent attacks
Low-dose aspirin is used less consistently by blacks than whites for the primary prevention of cardiovascular disease

Fewer Blacks Use Aspirin Therapy for Primary Prevention of CVD

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Low-dose aspirin linked to trend toward reduced risk for ischemic cardiac disease in whites, not blacks
Long-term use of low-dose aspirin may reduce the risk for dementia in women with type 2 diabetes

Low-Dose Aspirin May Cut Dementia Risk in Women With Diabetes

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However, no effect seen for lowering dementia risk in men with type 2 diabetes
Aspirin use three or more times per week is associated with reductions in all-cause

Aspirin Use May Reduce Cancer, All-Cause Mortality in Seniors

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Aspirin use three or more times per week tied to reduced all-cause, cancer, GI cancer, CRC mortality
Aspirin is associated with a reduced rate of aneurysm growth for patients with multiple intracranial aneurysms

Aspirin May Slow Growth of Multiple Intracranial Aneurysms

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Aspirin linked to decreased rate of aneurysm growth in patients with multiple intracranial aneurysms
Ticagrelor alone results in less bleeding than ticagrelor plus aspirin among high-risk patients who have undergone percutaneous coronary intervention and received dual antiplatelet therapy for three months

Less Bleeding With Ticagrelor Alone in High-Risk Patients

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Less bleeding with ticagrelor alone versus ticagrelor plus aspirin for patients after PCI
Nonsteroidal anti-inflammatory drugs are correlated with better overall survival in patients with head and neck squamous cell carcinoma

ASTRO: NSAIDs May Offer Benefit to Head & Neck Cancer Patients

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Benefit not significant for aspirin use in patients with non-small cell lung cancer undergoing SBRT
Patients with chronic coronary artery disease or peripheral artery disease treated with the combination of rivaroxaban and aspirin face a greater risk for bleeding versus patients treated with aspirin alone

Combo Antithrombotic Therapy Increases Bleeding Risk

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Greatest risk seen in first year of treatment, but benefits of combo therapy continue after one year
Aspirin for primary prevention of cardiovascular disease is likely to result in net benefit for some patients

Aspirin for Primary Prevention May Offer Net Benefit for Some

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Subgroups with net benefit had higher baseline CVD risk, higher levels of most established CVD risk factors