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Low-dose aspirin significantly lowers cardiovascular disease risk but increases the risk for bleeding

Low-Dose Aspirin Lowers CVD Risk but Raises Bleeding Risk

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Authors used umbrella review method to explore health outcomes associated with low-dose aspirin
For older adults

Low-Dose Aspirin Does Not Prevent Depression in Older Adults

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No significant difference seen in incidence rate of new CES-D-10 scores of ≥8 for aspirin, placebo
Regular aspirin use is associated with a lower risk for colorectal and other digestive tract cancers

Regular Aspirin Use Tied to Lower Risk for Digestive Tract Cancers

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Favorable effect increases with longer duration of use, and, for colorectal cancer, with increasing dose
For relatively healthy older individuals

Daily Low-Dose Aspirin Does Not Cut Dementia Risk in Seniors

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Risks for dementia, probable Alzheimer disease, MCI not reduced by low-dose aspirin versus placebo
Low-dose aspirin is associated with a reduced risk for hepatocellular carcinoma among patients with chronic viral hepatitis

Risk for Liver Cancer Down With Low-Dose Aspirin in Hepatitis B, C

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Risk for 10-year liver-related mortality also lower among aspirin users with chronic hepatitis B or C
In early bereavement

Short-Term Medications May Cut Risk for ‘Broken Heart’ Syndrome

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Combination of low-dose β-blocker and aspirin may reduce heightened CV risk in early bereavement
Among nulliparous women with singleton pregnancies from low-income and middle-income countries

Low-Dose Aspirin Cuts Preterm Delivery in Nulliparous Women

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Findings seen among women with singleton pregnancies in low-, middle-income countries
Aspirin may not be effective for primary prevention of cardiovascular disease and cancer mortality

Aspirin May No Longer Have Effect in Primary CVD Prevention

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Also no significant decrease seen in cancer death in studies from 2005 onward
Evidence supports the use of high-dose aspirin for treating acute migraine and low-dose aspirin for prevention of recurrent attacks

Evidence Supports Use of High-Dose Aspirin for Migraine

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High-dose aspirin safe, effective for acute migraine; low-dose aspirin can prevent recurrent attacks
Low-dose aspirin is used less consistently by blacks than whites for the primary prevention of cardiovascular disease

Fewer Blacks Use Aspirin Therapy for Primary Prevention of CVD

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Low-dose aspirin linked to trend toward reduced risk for ischemic cardiac disease in whites, not blacks