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Daily aspirin might extend survival for patients with cancers of the gastrointestinal tract

More Evidence Daily Aspirin May Protect Against GI Cancer

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Four-year study found survival doubled for GI cancer patients who took low-dose pill each day
The U.S. Preventive Services Task Force has concluded that the benefits and harms of low-dose aspirin for prevention of cardiovascular disease and cancer vary by patient age. These findings form the basis of a draft recommendation statement published online Sept. 14 by the USPSTF.

USPSTF Recommendations for Aspirin Use Vary by Age

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Recommended for some patients aged 50 to 59 years; insufficient evidence for those <50, ≥70
Regularly taking low-dose aspirin or other nonsteroidal anti-inflammatory drugs may lower long-term risk of colorectal cancer

Low-Dose Aspirin, Other NSAIDs May Lower Colorectal Cancer Risk

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Findings for consistent use over 5 or more years
About seven in 10 Americans with a history of cardiovascular disease or stroke regularly take aspirin

CDC: Aspirin Use Common Among Americans With Heart Disease

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Clinical and community-based approaches should be used to increase aspirin use among low-use groups
Dual antiplatelet therapy (DAPT) continued beyond six months after drug-eluting stent implantation is associated with reduced stent thrombosis and myocardial infarction but also increased bleeding and all-cause mortality as compared to shorter-term DAPT therapy

Review: Short vs. Long Duration Dual Antiplatelet Tx After Stent

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Longer DAPT linked to reduced stent thrombosis and myocardial infarction, increased bleeding, mortality
Aspirin use is associated with slower progression of percent emphysema on computed tomography

ATS: Aspirin Use Linked to Slower Progression of Emphysema

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Slower progression of percent emphysema on CT after adjustment for multiple variables
Slightly more than half of middle-aged adults and seniors in the United States take aspirin daily

Over Half of Middle-Age, Older Americans Take Daily Aspirin

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Having discussed aspirin with provider is the strongest predictor of regular use
Taking aspirin regularly over several years may help prevent gastrointestinal cancers

AACR: Regular Aspirin Use Linked to Lower GI Cancer Risk

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Greatest benefit from aspirin required taking it for at least 16 years
Aspirin use does not appear to reduce the risk of mortality associated with prostate cancer

Aspirin Use Not Found to Benefit Prostate Cancer Mortality

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Increased risks of mortality restricted to aspirin use after the diagnosis of prostate cancer
For patients with ischemic heart disease

Individual Short-Term Responses to Antiplatelet Therapy Vary

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Variability within individuals from pre-discharge to one week after discharge, but not thereafter