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Tag: Arthritis: Osteo

Cerebral palsy is associated with an increased risk for osteoporosis and osteoarthritis

Adults With Cerebral Palsy at Higher Risk for Osteoporosis

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U.K. study also shows association between CP and osteoarthritis when adjusting for other factors
For patients with osteoarthritis of the knee or hip

Tanezumab Improves Scores for Pain, Function in Osteoarthritis

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Improvements in mean WOMAC Pain, Physical Function scores for osteoarthritis of knee or hip
After six months

Higher Disease Burden for OA Than RA After Six Months

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Similar disease burden seen at presentation for osteoarthritis, rheumatoid arthritis
Knee pain is not associated with daily walking levels in individuals with mild-to-moderate

Knee Pain Not Tied to Activity Levels in Knee Osteoarthritis

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Neither inverted KOOS-pain nor P4 pain scale tied to physical activity
The initial prescription of tramadol compared with commonly prescribed nonsteroidal anti-inflammatory drugs may be associated with increased all-cause mortality among patients with osteoarthritis

Tramadol May Up Mortality Risk in Osteoarthritis Patients

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Findings for those initially prescribed tramadol compared with commonly prescribed NSAIDs
The American Academy of Orthopaedic Surgeons hip preservation surgery appropriateness classification system is driven almost entirely by age and radiographic hip osteoarthritis evaluation

Hip Preservation Appropriateness Guidelines May Be Limited

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Patient age, radiographic OA severity dominate prediction of hip preservation sx appropriateness
There is substantial variation across states in rates of long-term opioid therapy among patients with advanced osteoarthritis

Long-Term Opioid Use With OA Varies Across States

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Variance not fully explained by differences in access to health care providers or patient characteristics
The presence of Heberden's nodes in finger joints may also indicate structural damage associated with knee osteoarthritis

Heberden’s Nodes in Fingers Tied to Knee Osteoarthritis

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Significant associations seen between presence of HNs and MRI measures of knee arthritis
Radiographic knee osteoarthritis is associated with an increased risk for mortality from cardiovascular disease

Radiographic Knee Osteoarthritis Tied to Increased Risk for Death

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Risk higher for cardiovascular disease, diabetes, renal mortality; lower risk for cancer mortality
For postmenopausal women

Prevalence of Knee OA Lower With Menopausal Hormone Therapy

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Odds ratio for knee osteoarthritis was 0.7 in MHT group versus non-MHT group in multivariable model