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Tag: Arthritis: Osteo

In the 2019 American College of Rheumatology/Arthritis Foundation Guideline

Treatment Guidelines Updated for Hand, Hip, Knee Osteoarthritis

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Strong recommendations made for self-efficacy/self-management, tai chi, topical NSAID for knee, hand OA
A novel cathepsin K inhibitor

MIV-711 No Better Than Placebo for Pain Relief in Knee OA

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But significant reductions seen in medial femoral bone area progression, medial femoral cartilage thinning
Opioids offer minor pain relief and functional benefits in patients with osteoarthritis

ACR: Opioids Offer Only Minor Pain Relief in Osteoarthritis

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Opioids have no impact on QoL or depression; smaller benefits seen for pain for strong versus weak opioids
Osteoarthritis of the hip and/or knee increases the risk for social isolation in older

Knee, Hip Arthritis Increase Risk for Social Isolation in Elderly

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Findings based on multicountry, European study
For patients with knee osteoarthritis

Physical Therapy, Lifestyle Advice Underused in Knee OA

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2007 to 2015 saw increase in use of NSAID prescriptions from orthopedists, primary care doctors
An experimental growth factor therapy

Experimental Growth Factor May Aid Knee Osteoarthritis

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However, clinical significance uncertain as patients did not report symptom improvement
It may be possible to identify persons at risk for suffering a worsening in health-related quality of life due to knee osteoarthritis

Risk Factors ID’d for Worse QOL From Knee Osteoarthritis

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Female gender, overweight, smoking, knee pain, lower income tied to rapidly worsening quality of life
Osteoarthritis is an independent risk factor for increased cardiovascular disease

NSAIDs Contribute to Increased CVD Risk in Osteoarthritis

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Considerable proportion of increased CHF, IHD, and stroke risk mediated by NSAID use
The risk for cardiovascular deaths is increased among patients with knee and hip osteoarthritis

Risk for Cardiovascular Deaths Increased With Hip, Knee OA

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No increased mortality found for most causes of death
Breaches of recommended infection prevention practices have been identified in an outbreak of septic arthritis cases after intra-articular injections performed in a private outpatient facility

Safety Practice Violations ID’d in Septic Arthritis Outbreak

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Multiple breaches included inadequate hygiene, unsafe injection practices, poor cleaning, disinfection