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Tag: Antidepressants

Use of antidepressants in pregnancy is not associated with increased signs of irritability

Antidepressants in Pregnancy Don’t Affect Newborn Behavior

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Newborns aren't more likely to be irritable, hard to feed, or sleepless, researchers say
Obesity and sex are differential predictors of acute remission for commonly used antidepressant medications

Obesity, Sex Predict Remission for Antidepressant Medications

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Females, but not males, with higher BMI more likely to remit, regardless of medication type
Taking antidepressants during pregnancy doesn't appear to raise a child's risk of autism

Link Between Antidepressant Use in Pregnancy, Autism Challenged

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After accounting for other factors that increase risk, the association disappeared
The serotonin reuptake inhibitor citalopram is associated with making more healthy food choices

Single Dose of SSRI Prompted Healthy Food Choices During Test

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Citalopram increased choices of more versus fewer healthy foods relative to placebo
For patients undergoing total hip and total knee arthroplasty

AAOS: SSRI Use Linked to Lower Risk of Revision in THA, TKA

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Significantly lower risk of revisions, aseptic revisions; no reduction in risk of prosthetic joint infections
Antidepressant treatment efficacy varies for empirically-defined clusters of symptoms

Antidepressant Efficacy Varies for Depressive Symptom Clusters

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Most drugs more effective for core emotional symptoms than for sleep, atypical symptoms
Up to one-third of antidepressants are prescribed for pain

Off-Label Antidepressant Use Common, but Evidence Lacking

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Trazodone for insomnia most common off-label use for antidepressants
For patients with chronic depression

Panic Disorder May Up Odds of Depression Rx Side Effects

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Comorbid panic disorder tied to increased likelihood of side effects during treatment for depression
For older adults with late-life major depression

Antidepressants + Exercise Beneficial in Late-Life Depression

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Characteristics associated with remission for AD + PE include age 75 years and older, polypharmacy
Pharmacogenetic analysis can help optimize clomipramine doses in patients who do not respond to standard-dose treatment

Pharmacogenetic Analyses Can Optimize Clomipramine Dosing

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Case report of woman with depressive episode who did not respond to standard dose of clomipramine