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Tag: Antidepressants

Antidepressant prescribing is associated with long-term increased risk of weight gain

Antidepressant Prescribing Linked to Lasting Weight Gain

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Risk of weight gain remained increased during at least six years of follow-up
Children with prenatal exposure to serotonin reuptake inhibitors have better executive function at age 12 years

Executive Function Improved With Prenatal Exposure to SSRIs

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Better EF skills in 12-year-olds exposed to prenatal SSRI, even controlling for maternal depressive sx
Prenatal exposure to a selective serotonin reuptake inhibitor is associated with fetal brain development

Prenatal Exposure to SSRI Tied to Fetal Brain Development

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Significant gray matter volume expansion in right amygdala and right insula in SSRI-exposed infants
A substantial proportion of non-pregnant women of childbearing age have untreated depression

Depression Seen in One in 20 Childbearing-Aged Women

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Yet, antidepressant use is low in those with minor and major depression
A low risk of serotonin syndrome is seen in association with concomitant use of triptans and selective serotonin reuptake inhibitor or selective norepinephrine reuptake inhibitor antidepressants

Low Risk of Serotonin Syndrome for Triptans + SSRI/SNRI

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Researchers question FDA advisory warning on risk of concomitant use
For adults with major depressive disorder

21 Reviewed Antidepressants Top Placebo for Major Depression

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Agomelatine, amitriptyline, escitalopram are among most effective agents in head-to-head trials
Antidepressant medication adherence is associated with cessation of long-term prescription opioid use among patients with non-cancer pain

Treating Depression Found to Up Successful Opioid Cessation

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Taking antidepressants helped non-cancer pain patients successfully stop long-term opioid use
Paternal use of selective serotonin reuptake inhibitors before conception is associated with increased risk of attention-deficit/hyperactivity disorder in offspring

Preconception Paternal SSRI Use Linked to ADHD in Offspring

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Slightly increased ADHD risk in children born to fathers using SSRI in the three months preconception
For youths with depression

Treatment Trajectories Vary for Children With Depression

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Most common class got psychotherapy monotherapy, and had lowest incidence of attempted suicide
A psychosocial intervention can improve early adherence to antidepressants among middle-aged and older adults

Psychosocial Intervention Ups Adherence to Antidepressants

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Treatment Initiation and Participation Program improves early adherence among older patients