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Tag: Antidepressants

Most Primary Care Pediatricians Appropriately Prescribing SSRIs

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Pediatricians generally document appropriate indications for starting medication and prescribe without subspecialist involvement

Telemedicine Aided Depression Care During Pandemic

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No adverse effects seen for antidepressant fulfillment; increases were seen in symptom screening

Antidepressant Augmentation Examined in Seniors With Depression

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Improvement in well-being and remission seen with aripiprazole-augmentation of existing antidepressants

Evidence for Efficacy of Antidepressants for Pain Is Limited

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In 11 comparisons, antidepressants were efficacious, but they were inefficacious or evidence was inconclusive for 31 comparisons

Antidepressants Have Small Benefit for Pain, Function in OA

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However, total adverse events occur more often in patients receiving antidepressants versus placebo

Antidepressants in Pregnancy Do Not Affect Child Neurodevelopment

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Only crude associations seen between risk for neurodevelopmental outcomes and exposure to antidepressants

Link Between Serotonin and Depression Questioned

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Hypothesis that depression is caused by low serotonin not supported; some evidence shows decrease in serotonin with antidepressant use

Serotonergic Antidepressants in Pregnancy Not Tied to Neonatal Seizures

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Maternal use of SSRIs, SNRIs in first trimester of pregnancy not linked to increased risk for neonatal seizures or childhood epilepsy in offspring

Antidepressants Not Tied to Long-Term Boost in Quality of Life

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No improvement seen in physical or mental health-related quality of life

Antidepressant Combos Compared to Monotherapy for Acute Depression

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Combinations using an antagonist of presynaptic α2-autoreceptors may be an option for depression that does not respond to monotherapy