Tag: Antidepressants
Evidence for Efficacy of Antidepressants for Pain Is Limited
In 11 comparisons, antidepressants were efficacious, but they were inefficacious or evidence was inconclusive for 31 comparisons
Antidepressants Have Small Benefit for Pain, Function in OA
However, total adverse events occur more often in patients receiving antidepressants versus placebo
Antidepressants in Pregnancy Do Not Affect Child Neurodevelopment
Only crude associations seen between risk for neurodevelopmental outcomes and exposure to antidepressants
Link Between Serotonin and Depression Questioned
Hypothesis that depression is caused by low serotonin not supported; some evidence shows decrease in serotonin with antidepressant use
Serotonergic Antidepressants in Pregnancy Not Tied to Neonatal Seizures
Maternal use of SSRIs, SNRIs in first trimester of pregnancy not linked to increased risk for neonatal seizures or childhood epilepsy in offspring
Antidepressants Not Tied to Long-Term Boost in Quality of Life
No improvement seen in physical or mental health-related quality of life
Antidepressant Combos Compared to Monotherapy for Acute Depression
Combinations using an antagonist of presynaptic α2-autoreceptors may be an option for depression that does not respond to monotherapy
Incident Psychotropic Use Down in Children in Second Quarter of 2020
Greatest decline in incident stimulant and anxiolytic/sedative-hypnotic medications was in quarter 2 of 2020
Many Psychiatric Patients Are Getting Risky Drug Gabapentin ‘Off-Label’
SSRIs Linked to Reduced Relative Risk for Mortality in COVID-19
Relative risks for mortality significantly reduced for any SSRI, fluoxetine, and fluoxetine or fluvoxamine
