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Tag: Anticoagulants

For patients receiving anticoagulants

Safety, Effectiveness of VKAs, DOACs Similar in General Practice

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Risk for overall bleeding lower with vitamin K antagonists, but risk for mortality increased compared with DOACs
Lower-gastrointestinal bleeding is associated with high risks for colorectal cancer in patients with atrial fibrillation treated with oral anticoagulation therapy

GI Bleeding in OAC-Treated A-Fib Patients Indicates CRC Risk

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Lower-GI bleeding tied to high absolute risks for CRC in patients receiving oral anticoagulants for a-fib
Time of day for taking warfarin makes no difference on the drug's effectiveness

Time of Day for Taking Warfarin Does Not Matter

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Morning or evening administration makes no difference on time outside target INR range
For patients aged 65 years or older with atrial fibrillation

Receipt of Anticoagulant Rx in ED Linked to Use at Six Months

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Findings seen in patients aged 65 years or older with atrial fibrillation who present to emergency department
For older patients with atrial fibrillation

AHA: Risk for Death Cuts Benefit of Oral Anticoagulants for A-Fib

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Findings seen among older patients with incident atrial fibrillation receiving warfarin or apixaban
Among older patients undergoing hip or knee replacement

Low-Intensity Warfarin Not Noninferior in Hip, Knee Surgery

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Noninferiority not found compared with standard-intensity prophylaxis with hip or knee arthroplasty
Patients who restart their blood thinners after a gastrointestinal bleed have a lower risk for dying within the next two years even though they have a higher risk for recurrent gastrointestinal bleeding

Patients Should Restart Blood Thinners After GI Bleed

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Lower risk for ischemic events and death outweigh risk for another bleeding event
The postoperative risk for pulmonary embolism extends more than six weeks for six types of surgery

Pulmonary Embolism Risk Elevated for More Than Six Weeks Postop

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Findings based on six common surgery types in large French study
In thrombotic antiphospholipid antibody syndrome

Study Compares Anticoagulants for Antiphospholipid Syndrome

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Authors find rivaroxaban not noninferior to vitamin K antagonists for secondary thromboprophylaxis
Having a pharmacist in the emergency department significantly shortens the time to administration of treatment to reverse anticoagulation in patients with life-threatening bleeds or the need for urgent procedures

Pharmacist in ED Cuts Time to Tx to Reverse Anticoagulation

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Time to 4F-PCC shorter for patients who have life-threatening bleeding, need urgent procedures