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Tag: Anticoagulants

Two of three planned adaptive phase 3 clinical trials evaluating the safety and effectiveness of varying types of blood thinners to treat adults diagnosed with COVID-19 have launched

NIH Launches Clinical Trials of Antithrombotics for COVID-19

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Adaptive design allows evaluation of various doses, types of blood thinners in outpatients, inpatients
Genotyping may provide some clinical benefit in prescribing antiplatelet therapies for patients undergoing percutaneous coronary intervention

CYP2C19 Genotyping May Aid Antiplatelet Prescribing

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Benefit only seen for composite outcome, not for major or minor bleeding incidents
Among hospitalized patients with COVID-19

Mortality, Intubation Rates Lower With Anticoagulation in COVID-19

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Thromboembolic disease that was not suspected clinically identified in 42 percent of autopsies
Despite anticoagulant prophylaxis

High Rates of DVT Seen in Critically Ill COVID-19 Patients

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Authors call for prompt detection and early anticoagulant therapy
For patients with atrial fibrillation

Osteoporotic Fracture Risk Lower for DOAC Than Warfarin in A-Fib

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No differences seen in fracture risk in head-to-head comparisons of direct oral anticoagulants
For patients hospitalized with COVID-19

Anticoagulation May Improve Outcomes in COVID-19 Patients

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Longer duration of AC treatment linked to reduced risk for mortality in hospitalized patients
Prevention

Thromboembolic Complications in COVID-19 Discussed

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All hospitalized COVID-19 patients should be started on prophylactic low-molecular-weight heparin
Implementation of an anticoagulation protocol reduces blood clots in patients with traumatic brain injury

Quality Improvement Effort Cuts Blood Clots in Brain Injury Patients

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Prophylactic anticoagulation protocol improves patient outcomes
Following nonmajor orthopedic surgery of the lower limb

Rivaroxaban Prevents VTE After Lower-Limb Surgery

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Rivaroxaban superior to enoxaparin for preventing major VTE after nonmajor orthopedic surgery
For patients with atrial fibrillation after percutaneous coronary intervention

Dual Therapy Linked to Lower Bleeding Risk in A-Fib After PCI

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Low-certainty evidence showed inconclusive effects for all-cause mortality, cardiovascular mortality, MI