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HealthDay Reports: Why Is Coronavirus a Bigger Worry for People With Diabetes?

Early Anticoagulation May Not Up Survival in Severe COVID-19

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Venous thromboembolism seen in 6.3 percent and major bleeding seen in 2.8 percent of critically ill COVID-19 patients

Full-Dose Heparin May Aid Moderately Ill COVID-19 Patients

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Interim results show improvement in primary end point of need for ventilation, other organ-supportive interventions

Fluvoxamine Linked to Reduction in Clinical Deterioration in COVID-19

Anticoagulants Not Tied to Higher Risk for GI Bleed in COVID-19

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3 percent of hospitalized COVID-19 patients experience gastrointestinal bleeding

Ongoing Anticoagulant Use Does Not Avert Severe COVID-19

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No reduction seen in risks for hospital admission, intensive care unit admission, or death due to COVID

High-Dose Anticoagulation May Not Aid COVID-19 Patients

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No significant benefit seen for high-dose versus standard anticoagulation therapies, may be harmful

Two of three planned adaptive phase 3 clinical trials evaluating the safety and effectiveness of varying types of blood thinners to treat adults diagnosed with COVID-19 have launched

NIH Launches Clinical Trials of Antithrombotics for COVID-19

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Adaptive design allows evaluation of various doses, types of blood thinners in outpatients, inpatients
Genotyping may provide some clinical benefit in prescribing antiplatelet therapies for patients undergoing percutaneous coronary intervention

CYP2C19 Genotyping May Aid Antiplatelet Prescribing

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Benefit only seen for composite outcome, not for major or minor bleeding incidents
Among hospitalized patients with COVID-19

Mortality, Intubation Rates Lower With Anticoagulation in COVID-19

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Thromboembolic disease that was not suspected clinically identified in 42 percent of autopsies
Despite anticoagulant prophylaxis

High Rates of DVT Seen in Critically Ill COVID-19 Patients

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Authors call for prompt detection and early anticoagulant therapy
For patients with atrial fibrillation

Osteoporotic Fracture Risk Lower for DOAC Than Warfarin in A-Fib

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No differences seen in fracture risk in head-to-head comparisons of direct oral anticoagulants