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Tag: Anticoagulants

Bleeding Higher With Standard-Dose DOACs in Nonvalvular A-Fib

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Higher rate of bleeding seen with standard- versus reduced-dose DOACs in patients 65 years and older

Incident A-Fib Linked to Increased Risk of Mild Cognitive Impairment

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Risk of MCI not increased for patients with incident a-fib receiving digoxin treatment or anticoagulant and amiodarone treatment

DOACs Reduce Dementia Risk Versus Warfarin in A-Fib

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Significant reductions were seen in dementia risk for rivaroxaban, apixaban, and dabigatran versus warfarin in network meta-analysis

Apixaban Has Lower Bleeding Risk for Initial Anticoagulation for Venous Thromboembolism

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During extended treatment, bleeding risk was similar for apixaban and rivaroxaban

Prolonged Direct Oral Anticoagulants Beneficial for Preventing Recurrent VTE

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Findings seen among adults prescribed warfarin, DOACs beyond six months after acute venous thromboembolism

Ticagrelor-Acetylsalicylic Acid More Beneficial for Obese With Minor Stroke, TIA

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Significantly lower rate of stroke within 90 days seen for ticagrelor-ASA versus clopidogrel-ASA for those carrying CYP2C19 loss-of-function allele

Anticoagulants Do Not Reduce Arterial Thrombotic Event Risk in Cancer

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No reduction seen in risk of antithrombotic events but increased risk of major and minor bleeding

Benefits of Indefinite Anticoagulant Unclear After First VTE

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Indefinite anticoagulation prevented recurrent VTE events, but induced major bleeding events

Catheter-Directed Thrombolysis Beneficial for Pulmonary Embolism

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Systematic review showed risk for death and major bleeding complications was lower for catheter-directed thrombolysis than systemic thrombolysis

ASCO: Direct Oral Anticoagulant Therapy Feasible for Cancer Patients

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Direct oral anticoagulants noninferior to low-molecular-weight heparin for venous thromboembolism prevention