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Tag: Anticoagulants

There is a probable interaction between paritaprevir/ritonavir/ombitasvir+dasabuvir plus ribavirin with warfarin

Probable Interaction ID’d for PrOD, Ribavirin With Warfarin

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Case report shows probable interaction for ribavirin with paritaprevir/ritonavir/ombitasvir+dasabuvir
Some patients with atrial fibrillation who have implanted pacemakers or defibrillators may not always need anticoagulation

Researchers Say Not All A-Fib Patients Need Anticoagulation

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If episodes of atrial fibrillation are brief, risk of stroke is low
Pharmacist-managed warfarin anticoagulation therapy is associated with improved patient satisfaction

Patient Satisfaction Up With Pharmacist-Managed Warfarin Tx

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But no significant improvement in mortality, prevention of bleeding, thrombosis events
For adults with atrial arrhythmia after Fontan operation

Anticoagulation Cuts TEC Rate in Adults After Fontan Surgery

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Reduction in thrombotic, embolic complication rate among adults with atrial arrhythmia after Fontan
Among patients with atrial fibrillation

Warfarin Persistence Higher Than Previously Reported in A-Fib

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Risk of discontinuation increased with previous intracranial bleeding, excessive alcohol use, anemia
For acute major bleeding within 18 hours after factor Xa inhibitor administration

Andexanet Bolus, Infusion Cuts Anti-Factor Xa Activity

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Findings in patients with acute major bleeding associated with factor Xa inhibitors
Physician-perceived frailty and low life expectancy are the main reasons for warfarin discontinuation in elderly patients

Physician-Perceived Frailty Tied to Warfarin Discontinuation

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Discontinuation associated with increased risk of death and adverse events in very elderly
For patients with atrial fibrillation at moderate to high risk of stroke

DAPT Use Variable in Patients With A-Fib at Risk of Stroke

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Dual antiplatelet therapy used in variable manner; most patients remain on study drug after PCI
Just over two-thirds of patients retain an "acceptable" amount of key information following warfarin counseling

One-Third of Patients Don’t Retain Important Warfarin Info

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There is further drop off in information retention six weeks after initial counseling
Advice of regulatory authorities released in 2009 and 2010 regarding safety concerns for concomitant use of clopidogrel and certain proton pump inhibitors (PPIs) was partially followed

Many Still Prescribe Concomitant (Es)omeprazole, Clopidogrel

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Patients on clopidogrel prescribed omeprazole or esomeprazole despite safety warnings