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Factors ID’d for Eventual Surgery in Patients With Appendicitis

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Presence of an appendicolith increases risk for undergoing appendectomy after starting antibiotic therapy for acute appendicitis

Fosfomycin Not Noninferior to Comparators for Bacteremic UTI

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Fosfomycin not noninferior to ceftriaxone or meropenem for bacteremic urinary tract infection due to multidrug-resistant E. coli in adults

Pediatric Antibiotic Prescribing Dropped During Pandemic

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Decrease in antibiotic prescriptions in pediatric primary care driven by reduced volume of visits for respiratory tract infections

Antibiotic Choices for Skin, Soft Tissue Infections Vary by Race

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Compared with White inpatients, Black inpatients less likely to receive cefazolin, more likely to receive clindamycin for SSTIs

SSRIs Linked to Reduced Relative Risk for Mortality in COVID-19

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Relative risks for mortality significantly reduced for any SSRI, fluoxetine, and fluoxetine or fluvoxamine

ACS: Surgery May Follow Initial Antibiotic Therapy for Appendicitis

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At one and two years, 40 and 46 percent of patients initially receiving antibiotics underwent subsequent appendectomy

Antibiotic Dispensing Decreased After COVID-19 Restrictions

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36 percent reduction seen in antibiotic dispensing after COVID-19 restrictions; large reduction found in antibiotics for RTIs

Most Preprocedural Urinalyses Represent Low-Value Care

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Between six and 28 percent of preprocedural urinalyses that were not indicated were followed by an antibiotic prescription

Shorter Course of Antibiotics Noninferior for UTI in Afebrile Men

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Seven days of antibiotics noninferior to 14-day course for resolution of symptoms among afebrile men with urinary tract infection

Non-Antimicrobial Drugs Tied to Drug-Resistant Bacterial Infection

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Proton pump inhibitors, beta-blockers, antimetabolites linked to infection with antibiotic-resistant bacteria