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The interaction between antibiotics and human growth and obesity is explored in a historical perspective piece published in the Jan. 17 issue of the Annals of Internal Medicine.

Interaction Between Antibiotics, Obesity Is Complex

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Since the 2000s, attention has turned toward understanding role of abx, microbiome in obesity
A single fecal transplant delivered by enema is apparently no more effective than oral antibiotics in treating recurring cases of Clostridium difficile infection

Fecal Transplant No Better Than Oral Antibiotic for C. difficile

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In direct comparison, researchers found no real difference between transplant, antibiotic treatment
For children with acute otitis media with tympanostomy tubes

Ciprofloxacin Plus Fluocinolone More Effective for Peds AOMT

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More effective than ciprofloxacin or fluocinolone alone for acute otitis media w/tympanostomy tubes
Repeat treatment with the nonsystemic antibiotic rifaximin is effective in patients with relapsing symptoms of diarrhea-predominant irritable bowel syndrome

Rifaximin Effective for Repeat Treatment of IBS With Diarrhea

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Findings for repeat treatment of relapsing symptoms in diarrhea-predominant irritable bowel syndrome
Reduced-duration antimicrobial treatment is associated with less favorable outcomes among infants with acute otitis media

Shortened Abx Inferior for Acute Otitis Media in Children <2 Years

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Greater likelihood of clinical failure, higher symptom score for five-day course of amoxicillin-clavulanate
The 2011 clinical practice guideline on urinary tract infection in young children has been reaffirmed

Clinical Practice Guideline on UTI in Febrile Young Reaffirmed

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2011 CPG on urinary tract infection in infants and young children reaffirmed after review of literature
Among U.K. general practitioners

Acne Treatment Often Not in Line With Current Guidelines

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Mean therapy duration was 175.1 days; 62 percent of antibiotic courses not given with topical retinoid
Use of a computerized physician order entry system can improve compliance with antimicrobial restriction policies

Computer Order Entry System Ups Antimicrobial Policy Compliance

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After introduction of system, improvement seen in surveillance, compliance, approvals
For children with complicated pneumonia

IV, Oral Antibiotics Compared for Complicated Pneumonia

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No difference in post-discharge treatment failure; more complications, adverse drug events for PICC
There is poor understanding of penicillin tolerance

ACAAI: Many Clinicians Lack Understanding of PCN Tolerance

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And >80 percent of providers, advanced practitioners have never or rarely consulted an allergist