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A new review

Review Shares Best Practices for Evaluating Penicillin Allergy

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Verifying reported allergies necessary to improve outcomes, prevent antibiotic resistance
Dermatologists' use of antibiotics to treat inflammatory skin conditions like acne and rosacea is decreasing

Dermatologists’ Rx for Antibiotics Dropped From 2008 to 2016

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However, rising use of antibiotics after dermatologic surgical visits is concerning
Most emergency visits by children occur at nonpediatric emergency departments

Antibiotics Prescribed for Children More Often at Nonpediatric EDs

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Frequency of guideline-concordant prescribing for respiratory conditions lower at nonpediatric EDs
Patients taking fluoroquinolones may be at higher risk for ruptures or tears in the aorta

FDA: Fluoroquinolones Tied to Heart Vessel Ruptures, Tears

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Patients at risk include those with hypertension or certain genetic disorders and the elderly
Antibiotic use in children <24 months of age is associated with a slightly higher body weight at 5 years of age

Early Antibiotic Use May Be Tied to Higher Childhood Body Weight

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Antibiotics before age 2 associated with very small increase in body weight at 5 years of age
Following the 2007 American Heart Association update of recommendations for antibiotic prophylaxis (AP) to prevent infective endocarditis (IE)

AHA: After 2007 Recs, Increase Seen in Infective Endocarditis

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Twenty percent drop in antibiotic prophylaxis, 177 percent increase in IE incidence for high-risk
Almost half of parents report saving leftover antibiotics

AAP: Parents Frequently Save Leftover Antibiotics

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Almost three-quarters of those saving antibiotics subsequently divert the antibiotics to others
Prescription of antibiotics and acid-suppressing medications in early childhood is associated with an increased risk for obesity

Antibiotics, Acid Suppressants in Infancy May Up Obesity Risk

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Prescription of antibiotics, acid-suppressing meds in first two years of life linked to childhood obesity
For complicated urinary tract infections caused by multidrug-resistant Gram-negative uropathogens

In Complicated UTI, Cefiderocol Noninferior to Imipenem-Cilastin

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Results from phase 2 study in patients with multidrug-resistant Gram-negative uropathogens
For patients with staphylococcal bacteremia

Algorithm-Defined Tx Duration Non-Inferior in Staph Bacteremia

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Non-inferior rate of clinical success for algorithm defining treatment duration versus usual care