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Patients hospitalized with pneumonia often receive excess antibiotic therapy

Hospitalized Pneumonia Patients Often Get Excess Antibiotics

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Vast majority of excess treatment occurs with antibiotics prescribed at discharge
Most U.S. adults have heard of and are concerned about antibiotic resistance

Most U.S. Adults Are Concerned About Antibiotic Resistance

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However, almost half of survey respondents have not taken antibiotics as prescribed in the past
Antibiotic stewardship interventions for acute respiratory infection can significantly reduce overuse in emergency departments and urgent care centers

Stewardship Intervention Can Cut Inappropriate Rx by a Third

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Findings observed for acute respiratory infection in emergency departments and urgent care centers
Children with community-acquired pneumonia often receive diagnostic testing and antibiotic therapy despite publication of guidelines against their routine use in 2011

Diagnostic Testing, Antibiotics Overused in Pediatric CAP

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Chest radiography ordered in 43 percent, antibiotics prescribed in 73.9 percent of community-acquired pneumonia visits
Antibiotic prophylaxis before dental procedures is unnecessary more than 80 percent of the time

Antibiotic Prophylaxis Before Dental Work Often Unnecessary

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Dentists write 10 percent of all prescriptions for antibiotics in the United States
A single dose of a prophylactic antibiotic is beneficial after operative vaginal birth and reduces the risk for confirmed or suspected maternal infection

Prophylactic Antibiotic Cuts Infection Risk After Operative Vaginal Birth

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Benefits seen following operative vaginal birth at 36 weeks of gestation or later
A single dose of gentamicin is an appropriate second-line therapy for gonorrhea resistant to a single dose of ceftriaxone

Gentamicin Appropriate Second-Line Therapy to Ceftriaxone for Gonorrhea

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Two weeks after treatment, infection cleared for 98, 91 percent treated with ceftriaxone versus gentamicin
Three months of azithromycin did not significantly reduce treatment failure among patients hospitalized for an acute exacerbation of chronic obstructive pulmonary disease

Impact of Azithromycin Studied in Acute Exacerbation of COPD

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Azithromycin leads to significant drops in treatment intensification and step-up in hospital care
For women in middle and late adulthood

Longer Duration of Antibiotic Use Tied to Risk for CVD in Women

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Risk for cardiovascular disease increased for women in middle, late adulthood with longer antibiotic use
For children with acute respiratory infections

Telemedicine Leads to More Antibiotic Rx for Pediatric Respiratory Infection

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More antibiotics prescribed with less guideline-concordant antibiotic management versus other settings