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Subcutaneous injection of H2 significantly improves type 2 diabetes mellitus-related outcomes in a mouse model

H2 Injection Aids Diabetes Outcomes in Animal Model

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Subcutaneous injection may be an effective means of administration
Commonly used hearing tests often fail to detect a prevalent form of inner ear damage

Hearing Tests May Miss Common Form of Hearing Loss

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Audiogram can appear normal even with damage to inner hair cells
In response to stimulation

Drug Combo May Help Combat Hearing Loss

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Lgr5-expressing cells differentiate into hair cells in high yield; >11,500 hair cells from single cochlea
A new vaccine for herpes simplex virus type 2 could be nearing human clinical trials

Early Study Results Promising for Genital Herpes Vaccine

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Two-pronged approach tested on lab monkeys, guinea pigs
An experimental drug

Experimental Drug May Simplify Macular Degeneration Treatment

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Animal tests showed fewer injections needed to treat age-related macular degeneration
Scientists are reporting some early success with a soft robotic device aimed at treating advanced heart failure. The findings have been published in the Jan. 18 issue of Science Translational Medicine.

Soft Robotic Sleeve Can Replicate Heart’s Natural Rhythm

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Device found to support heart function in a porcine model of acute heart failure
The amplitude of therapeutic revascularization associated with recombinant adeno-associated virus (5 × 1012 viral particles encoding thymosin beta 4) is reduced with diabetes mellitus

Diabetes May Impair Myocardial Proangiogenic Response

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Reduction in amplitude of therapeutic neovascularization via rAAV.Tβ4 in pig model
Ivermectin has anti-inflammatory properties that could be beneficial in treatment of T-cell mediated skin inflammatory diseases

Ivermectin Has Topical Anti-Inflammatory Properties

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Topical ivermectin improves allergic skin inflammation in murine model of atopic dermatitis
For midlife ovariectomized Long Evans rats

Duration of Estrogen Rx May Be Important Factor in Renal Health

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Long-term estradiol treatment induced renal and cardiac hypertrophy, reduced glomerular filtration
Vaginal tissue is particularly vulnerable to infection by RNA viruses

Vaginal Immune Response May Up Zika Risk in Women

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Findings suggest, when transmitted sexually, women are more susceptible to contracting RNA viruses