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Tag: Anesthesia

For older cancer patients undergoing major cancer surgery

Propofol May Decrease Delay in Neurocognitive Recovery

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Less delay versus sevoflurane general anesthesia in older patients undergoing major cancer surgery
For older patients undergoing hip fracture repair

Sedation Level Doesn’t Impact Delirium Risk After Hip Fx Repair

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In subgroup analysis, heavier versus lighter sedation doubled risk of delirium in low comorbid states
Anesthesia care team composition is not associated with surgical outcomes

No Outcome Differences Based on Anesthesia Team Make-Up

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No significant differences in mortality, length of stay, or inpatient spending seen
Intravenous acetaminophen does not decrease opioid utilization to a clinically significant threshold among colectomy patients

IV Acetaminophen Minimally Helpful for Colectomy Pain

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IV acetaminophen has similar effectiveness to oral doses and doesn't meaningfully cut opioid use
A machine-learning algorithm can predict hypotension during surgery based on high-fidelity arterial pressure waveform analysis

Algorithm Predicts Very Low Blood Pressure During Surgery

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Advance warning, even 10 to 15 minutes ahead, can reduce harm to patients
On the day of surgery it is practical to allow children to drink until one hour before anesthesia

Children Can Drink Clear Fluids Until One Hour Before Anesthesia

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No increased risk of pulmonary aspiration; less nausea, vomiting, thirst, hunger, anxiety reported
Dexmedetomidine prevents excessive γ-aminobutyric acid type A receptor function after anesthesia

Dexmedetomidine Cuts γ-Aminobutyric Acid Receptor Function

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Cuts etomidate-induced increase in α5 γ-aminobutyric acid type A receptor cell-surface expression
Regional anesthesia is associated with a lower opioid consumption in both knee and hip replacement surgeries

Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

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Findings based on comparison to general anesthesia for knee and hip arthroplasty
A restrictive fluid regimen is not associated with increased disability-free survival for patients at increased risk of complications during major abdominal surgery

Restricting Fluids Post Abdominal Surgery Doesn’t Up Survival

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Fluid restriction has no impact on disability-free survival; increases risk of acute kidney injury
Multiple exposures to anesthesia before the age of 3 years may have neuropsychological impacts

Anesthesia Before Age 3 Not Linked to Intelligence Deficits

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However, multiple early exposures associated with decreases in processing speed, fine motor abilities