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Tag: Anemia

Mitapivat Superior to Placebo for Pyruvate Kinase Deficiency

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Early, sustained, clinically significant hemoglobin response seen in 40 percent of patients receiving mitapivat versus none in the placebo group

Risks for Anaphylaxis Compared Among IV Iron Products

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Rates of anaphylaxis low for IV iron products, but risk for anaphylaxis increased with iron dextran and ferumoxytol compared with iron sucrose

Eltrombopag Augments Immunosuppression in Severe Aplastic Anemia

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Improvement seen in the rate, rapidity, strength of hematologic response in previously untreated patients with severe aplastic anemia

ASN: Daprodustat Noninferior to ESAs for Treating Anemia in CKD

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Randomized, open-label, phase 3 trials conducted in patients with chronic kidney disease undergoing, not undergoing dialysis

Many Pregnancies Affected by Iron Deficiency

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Yet, less than half of individuals have their ferritin levels checked during pregnancy

Roxadustat Treats Anemia in Non-Dialysis-Dependent CKD

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Pooled data show roxadustat versus placebo increases hemoglobin levels with an acceptable profile for cardiovascular safety

In a second edition of international guidelines

Guidelines Updated for Hereditary Hemorrhagic Telangiectasia

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Updated content covers six topic areas, including new areas of anemia, pediatrics, pregnancy and delivery
Most

Most Teens Recover Iron Stores One Year After Whole Blood Donation

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Less than half of blood donors with low ferritin at index achieved adequate stores within 12 months
Inhibition of interleukin-1β with canakinumab is associated with reduced incident anemia as well as improved hemoglobin levels among patients with baseline anemia

Interleukin-1β Inhibition Linked to Reduced Incidence of Anemia

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Among those with baseline anemia, hemoglobin levels improved with canakinumab versus placebo
For patients with lower-risk myelodysplastic syndromes with ring sideroblasts who have been receiving regular red-cell transfusions

Luspatercept Mitigates Anemia in Lower-Risk Myelodysplastic Syndromes

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Transfusion burden reduced in patients with lower-risk myelodysplastic syndromes with ring sideroblasts