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Tag: Alzheimer’s

Risk for Neurodegenerative Disease Increased for Soccer Players

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Increased risk seen for Alzheimer disease and other dementias, but no increase seen for motor neuron disease or Parkinson disease

Less Postmortem Alzheimer Disease Pathology Seen With MIND, Mediterranean Diets

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Global Alzheimer disease pathology lower in patients following these dietary patterns, specifically less beta-amyloid load

Certain Genetic Variant in Alzheimer Disease Linked to African Ancestry

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Increased risk for Alzheimer disease and younger age of onset seen with APOE ε3 R145C missense variation

Social Isolation Tied to Wide Variety of Dementia Risk Factors

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Social isolation may be a modifiable risk factor for preventing Alzheimer disease-related dementias, authors say

Plasma Biomarkers Identified for Detecting Presymptomatic Alzheimer Disease

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Plasma P-tau181, NfL, GFAP concentrations higher in mutation carriers versus noncarriers of autosomal dominant Alzheimer disease

Vascular Risk Factors Only Explain Part of Alzheimer Disease Risk for Blacks, Hispanics

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Barriers to health care access and other socioeconomic factors may increase vulnerability in racial/ethnic minorities

PTSD, TBI Interact With APOE ε4 to Raise Alzheimer, Dementia Risk

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Significant additive APOE ε4 interactions seen with PTSD and TBI in veterans of European ancestry

FDA Approves Second Drug for Alzheimer Disease, Despite Safety Concerns

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Approval of Leqembi comes after controversial approval in 2021 of Aduhelm, which met with criticism over concerns about that drug's effectiveness, safety, pricing

Natural Environments May Cut Hospitalization for Patients With Neurodegenerative Diseases

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Normalized difference vegetation index negatively associated with hospitalization for Alzheimer disease and related dementia, Parkinson disease

Congressional Report Slams FDA, Drugmaker Over Approval of Alzheimer Drug Aduhelm

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Controversy over Aduhelm stretches back to its June 2021 approval by the U.S. Food and Drug Administration