Tag: Alzheimer’s
Certain Genetic Variant in Alzheimer Disease Linked to African Ancestry
Increased risk for Alzheimer disease and younger age of onset seen with APOE ε3 R145C missense variation
Social Isolation Tied to Wide Variety of Dementia Risk Factors
Social isolation may be a modifiable risk factor for preventing Alzheimer disease-related dementias, authors say
Plasma Biomarkers Identified for Detecting Presymptomatic Alzheimer Disease
Plasma P-tau181, NfL, GFAP concentrations higher in mutation carriers versus noncarriers of autosomal dominant Alzheimer disease
Vascular Risk Factors Only Explain Part of Alzheimer Disease Risk for Blacks, Hispanics
Barriers to health care access and other socioeconomic factors may increase vulnerability in racial/ethnic minorities
PTSD, TBI Interact With APOE ε4 to Raise Alzheimer, Dementia Risk
Significant additive APOE ε4 interactions seen with PTSD and TBI in veterans of European ancestry
FDA Approves Second Drug for Alzheimer Disease, Despite Safety Concerns
Approval of Leqembi comes after controversial approval in 2021 of Aduhelm, which met with criticism over concerns about that drug's effectiveness, safety, pricing
Natural Environments May Cut Hospitalization for Patients With Neurodegenerative Diseases
Normalized difference vegetation index negatively associated with hospitalization for Alzheimer disease and related dementia, Parkinson disease
Congressional Report Slams FDA, Drugmaker Over Approval of Alzheimer Drug Aduhelm
Controversy over Aduhelm stretches back to its June 2021 approval by the U.S. Food and Drug Administration
PET Changes Similar for Alzheimer Disease, Down Syndrome
No difference seen in global PET amyloid burden between asymptomatic with Down syndrome, asymptomatic mutation carriers
Study Explores Impact of FDA Approval of Aducanumab on Trial Participation
Individuals who were independently aware of the FDA decision demonstrated reduced willingness to participate
