Tag: Alzheimer’s

Slows clinical progression at 76 weeks for those with low/medium tau and the combined low/medium and high tau pathology population

Higher appendicular lean mass also associated with increased cognitive performance

While Leqembi did help reduce mental decline compared with placebo, the drug has been linked to two deaths from brain bleeds

Those in highest quintile of total cholesterol, triglycerides had increased risk for AD and Alzheimer-related dementias

Improvement in global cognition seen for patients with Alzheimer disease/MCI, but no effects seen for healthy individuals, other patient populations

Association found between simulated real-life IADL and interactions of amyloid and early tau accumulation in cognitively normal seniors

Change in gut microbiome composition associated with β-amyloid and tau pathological brain biomarkers

Greater effect seen for patients aged 70 years and older at time of bacillus Calmette-Guerin vaccination

Drug makers will also have to gather and keep data in a registry showing how the drugs are working in the real world

Genetic predisposition to Alzheimer's also linked to increased risk of focal epilepsy with hippocampal sclerosis