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Tag: Alzheimer’s

Finger Prick, Venous Blood Can ID Key Alzheimer Disease Biomarkers

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Capillary and venous dry blood spot can identify glial fibrillary acidic protein, neurofilament light, phosphorylated tau

Excess Alzheimer, Related Dementia-Linked Mortality Increased During COVID-19

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Large increase seen in mortality with ADRD as underlying, contributing cause of death in pandemic year 1

Solanezumab Does Not Slow Cognitive Decline in Preclinical Alzheimer Disease

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Mean change in Preclinical Alzheimer Cognitive Composite score not significantly different at 240 weeks with solanezumab, placebo

Eastern, Southeastern U.S. Have Highest Prevalence of Alzheimer Disease

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Counties with the highest prevalence were Miami-Dade County in Florida, Baltimore County in Maryland, and Bronx County in New York

Donanemab Slows Clinical Progression in Early Alzheimer Disease

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Slows clinical progression at 76 weeks for those with low/medium tau and the combined low/medium and high tau pathology population

Appendicular Lean Mass Linked to Decrease in Alzheimer Risk

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Higher appendicular lean mass also associated with increased cognitive performance

FDA Gives Full Approval to Alzheimer Disease Drug Leqembi

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While Leqembi did help reduce mental decline compared with placebo, the drug has been linked to two deaths from brain bleeds

Variation in Total Cholesterol, Triglycerides Linked to Alzheimer Disease Risk

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Those in highest quintile of total cholesterol, triglycerides had increased risk for AD and Alzheimer-related dementias

Intranasal Insulin May Have Pro-Cognitive Benefits

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Improvement in global cognition seen for patients with Alzheimer disease/MCI, but no effects seen for healthy individuals, other patient populations

Instrumental Activities of Daily Living Test Could ID Alzheimer Disease

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Association found between simulated real-life IADL and interactions of amyloid and early tau accumulation in cognitively normal seniors