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Tag: Alzheimer’s

Antipsychotic Use Increased for Seniors With Alzheimer, Related Dementias

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Among patients with ADRD receiving care from a home health agency, antipsychotic use was tied to less improvement in activities of daily living

Alzheimer, Parkinson Disease Share Protective Association at HLA Locus

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Protective HLA-DRB1*04 subtypes bind strongly to aggregation-prone tau PHF6 sequence when acetylated at K311

Panel of 48 CSF Proteins Complements Existing Alzheimer Biomarkers

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CSF 48 panel plus existing biomarkers significantly improved diagnostic performance for outcomes studied

Routine Vaccines Can Cut Risk for Later Alzheimer Disease

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Findings seen for tetanus and diphtheria, shingles, and pneumococcus vaccines

Eligibility Limited for Anti-β Amyloid mAbs in Seniors With MCI

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Few older adults with MCI or mild dementia were eligible for lecanemab, aducanumab after applying clinical trial criteria

Racial/Ethnic Minorities Underrepresented in Alzheimer Neuroimaging Research

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Sample diversity has improved recently, with proportion of Blacks increasing from 3.39 percent in 1994-2017 to 8.29 percent in 2018-2022

Finger Prick, Venous Blood Can ID Key Alzheimer Disease Biomarkers

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Capillary and venous dry blood spot can identify glial fibrillary acidic protein, neurofilament light, phosphorylated tau

Excess Alzheimer, Related Dementia-Linked Mortality Increased During COVID-19

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Large increase seen in mortality with ADRD as underlying, contributing cause of death in pandemic year 1

Solanezumab Does Not Slow Cognitive Decline in Preclinical Alzheimer Disease

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Mean change in Preclinical Alzheimer Cognitive Composite score not significantly different at 240 weeks with solanezumab, placebo

Eastern, Southeastern U.S. Have Highest Prevalence of Alzheimer Disease

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Counties with the highest prevalence were Miami-Dade County in Florida, Baltimore County in Maryland, and Bronx County in New York