Tag: Alzheimer’s
Finger Prick, Venous Blood Can ID Key Alzheimer Disease Biomarkers
Capillary and venous dry blood spot can identify glial fibrillary acidic protein, neurofilament light, phosphorylated tau
Excess Alzheimer, Related Dementia-Linked Mortality Increased During COVID-19
Large increase seen in mortality with ADRD as underlying, contributing cause of death in pandemic year 1
Solanezumab Does Not Slow Cognitive Decline in Preclinical Alzheimer Disease
Mean change in Preclinical Alzheimer Cognitive Composite score not significantly different at 240 weeks with solanezumab, placebo
Eastern, Southeastern U.S. Have Highest Prevalence of Alzheimer Disease
Counties with the highest prevalence were Miami-Dade County in Florida, Baltimore County in Maryland, and Bronx County in New York
Donanemab Slows Clinical Progression in Early Alzheimer Disease
Slows clinical progression at 76 weeks for those with low/medium tau and the combined low/medium and high tau pathology population
Appendicular Lean Mass Linked to Decrease in Alzheimer Risk
Higher appendicular lean mass also associated with increased cognitive performance
FDA Gives Full Approval to Alzheimer Disease Drug Leqembi
While Leqembi did help reduce mental decline compared with placebo, the drug has been linked to two deaths from brain bleeds
Variation in Total Cholesterol, Triglycerides Linked to Alzheimer Disease Risk
Those in highest quintile of total cholesterol, triglycerides had increased risk for AD and Alzheimer-related dementias
Intranasal Insulin May Have Pro-Cognitive Benefits
Improvement in global cognition seen for patients with Alzheimer disease/MCI, but no effects seen for healthy individuals, other patient populations
Instrumental Activities of Daily Living Test Could ID Alzheimer Disease
Association found between simulated real-life IADL and interactions of amyloid and early tau accumulation in cognitively normal seniors