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Tag: Alzheimer’s

The first case of Alzheimer's disease (AD) diagnosed in a person with HIV suggests progressive dementia in older HIV+ individuals may be due to HIV-associated neurocognitive disorder

Novel Case of Alzheimer’s Reported in HIV+ Patient

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Amyloid PET imaging may help distinguish AD from HIV-associated neurocognitive disorder
Autosomal dominant Alzheimer's disease is associated with increased white matter hyperintensities on magnetic resonance imaging well before expected symptom onset

White Matter Hyperintensities Predate Alzheimer’s Onset

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White matter hyperintensity volume differences seen six years before symptoms
Neuronal heparan sulfates modulate brain amyloid-β clearance and aggregation in a mouse model of Alzheimer's disease

Neuronal Heparan Sulfates Play Role in Amyloid Pathology

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Removal of neuronal HS linked to reduction in Aβ oligomerization and deposition of amyloid plaques
Intellectual enrichment (high education and high midlife cognitive activity) has effects on biomarkers of Alzheimer's disease in older adults

Active Mind May Delay Alzheimer Symptoms, but Not Disease

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High midlife cognitive activity tied to lower amyloid deposition in APOE4 carriers with high education
High levels of perceived stress could be a risk factor for cognitive impairment and Alzheimer's disease

Perceived Stress May Increase Risk of Cognitive Decline

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Adults who perceived themselves to be under the most stress had 30 percent greater risk
Patients with early-stage Alzheimer's disease who consume two to three alcoholic drinks a day may have a reduced risk of mortality compared to those who consume one or fewer drinks a day

Moderate Drinking May Benefit Early-Stage Alzheimer’s Patients

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Two, three alcoholic drinks daily linked to reduced risk of death over three-year study period
Androgen deprivation therapy for prostate cancer might dramatically increase a man's risk of developing Alzheimer's disease

ADT for Prostate CA Tied to Increased Alzheimer’s Risk

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Research suggests dose-dependent effect
Seniors who walk more slowly may have higher amounts β-amyloid in their brains

Slow Gait in Seniors May Be Indicative of Alzheimer’s

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Researchers find higher levels of β-amyloid in brains of those who didn't move as fast as their peers
Raloxifene doesn't benefit cognition in women who have mild to moderate dementia due to Alzheimer's disease

Raloxifene Does Not Appear to Boost Cognition in Alzheimer’s

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Researchers find no cognitive benefits from raloxifene in women with mild to moderate dementia
A drug that combines dextromethorphan with quinidine might offer a safer option for calming the agitation that commonly affects people with Alzheimer's disease

Combo Drug May Calm Agitation in Alzheimer’s Patients

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Drug combines dextromethorphan with quinidine