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Tag: Alzheimer’s

A diagnosis of mild cognitive impairment is frequently associated with comorbid neuropathologies

Comorbid Neuropathies Common With MCI Diagnosis

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Mixed Alzheimer's disease neuropathic changes more frequent than pure ADNC among those with MCI
Women who use hormone therapy after menopause may not have a lower risk of developing Alzheimer's disease

Hormone Therapy Doesn’t Appear to Protect Against Alzheimer’s

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Possible benefit for long-term hormone therapy, but results not definitive
Developing hypertension in very old age may provide some protection from dementia

Hypertension Onset After Age 80 May Protect Against Dementia

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Association independent of antihypertensive medication use
Concussions may be associated with accelerated cortical thickness and memory decline in Alzheimer's disease-relevant areas

Concussions May Accelerate Alzheimer’s Disease Progression

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Brain trauma seems to speed up mental decline in patients at genetic risk for Alzheimer's
Effectiveness of statin use in Alzheimer's prevention may depend on the specific statin

Effect of Statins on Alzheimer’s May Depend on Gender, Race

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Type of statin used also makes a difference; no benefit seen for black men
Amyloid beta deposits in Alzheimer's patients might also negatively affect their heart muscle and increase their risk of heart failure

Amyloid Beta Deposits Can Affect Hearts of Alzheimer’s Patients

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Deposits can lead to compromised myocardial function
Home-based occupational therapy may not slow down the physical decline that comes with Alzheimer's disease

Occupational Tx of Little Benefit in Slowing Alzheimer’s Decline

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Patients, caregivers may reap some benefits, but study suggests no effect on everyday functioning
Early diagnosis of Alzheimer's disease in women may be more difficult than in men because older women tend to retain better verbal memory

Women’s Better Memory Skills May Delay Alzheimer’s Diagnosis

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Women tend to hold on to better verbal memory skills as they age compared to men
Physical function is associated with clinical and subclinical brain disease

Physical Function Tied to Clinical, Subclinical Neurological Disease

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Slow walking and weak handgrip linked to increased risk of Alzheimer's disease
Use of [18F]-AV-1451 positron emission tomography can potentially stage Alzheimer's disease

[18F]-AV-1451 Shows Staging Potential in Alzheimer’s

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Elevated [18F]-AV-1451 SUVR linked to volumetric loss in hippocampus, AD cortical signature regions