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Tag: Alzheimer’s

The use of idalopirdine does not improve cognition versus placebo over 24 weeks of treatment for patients with mild-to-moderate Alzheimer's disease

Idalopirdine May Not Improve Cognition in Mild Alzheimer’s

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Findings from three randomized trials show no improvement in cognition vs. placebo over 24 weeks
Low memory scores are an early marker of amyloid positivity

Memory Scores Limited As Alzheimer’s Screening Tool

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Scores are an early marker of amyloid positivity, but limited in value for those without dementia
The combination of environmental enrichment and magnesium-L-threonate is more effective than either treatment alone for improving cognition and spatial memory in a mouse model of Alzheimer's disease

Magnesium Boosts Environmental Enrichment in Alzheimer’s

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Combination of EE, magnesium-L-threonate more effective than either treatment alone in mouse model
In patients with type 2 diabetes

Retinal Sensitivity Linked to Cognitive Status in T2DM

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Retinal sensitivity assessed by microperimetry is correlated with neurodegeneration parameters
Women with a genetic predisposition for Alzheimer's disease face a 10-year window -- between ages 65 and 75 -- when they have far greater chances of developing the disease than men with similar genetic risks

Gender-Specific High-Risk ‘Window’ Seen in Alzheimer’s

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Women genetically predisposed to Alzheimer's more susceptible than men from 65 to 75 years of age
Increased blood pressure variability is associated with a higher risk of all-cause dementia

Blood Pressure Variability Linked to Risk of Dementia in Elderly

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Increased variability risk factor for dementia, vascular dementia, Alzheimer's, independent of BP
Distinguishing Alzheimer's disease from frontotemporal dementia may get easier using a transcranial magnetic stimulation approach

New, Noninvasive Method May Help Determine Dementia Type

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Transcranial magnetic stimulation could help discern Alzheimer's from frontotemporal dementia
For patients with type 2 diabetes mellitus

Fasting Plasma Glucose, HbA1c Linked to Alzheimer’s in T2DM

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Independent associations for FPG coefficient of variation and HbA1c CV in patients with T2DM

Alzheimer’s Association, July 16-20

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The Alzheimer's Association International Conference The annual meeting of the Alzheimer's Association was held from July 16 to 20 in London and attracted...
Amyloid beta (Aβ)38 has faster turnover kinetics than Aβ40 and Aβ42

AAIC: Turnover Kinetics Vary for Different Amyloid β Isoforms

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Half-life of Aβ isoforms about three hours; Aβ38 has faster turnover kinetics than Aβ40, Aβ42