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Tag: Alzheimer’s

Individuals with Alzheimer disease initiating antipsychotics have an increased risk for head injuries and traumatic brain injury

Antipsychotic Initiation Ups Risk for Head Injury, TBI in Alzheimer Disease

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TBI injury risk up for quetiapine versus risperidone users
The global intensity of the tau-positron emission tomography signal predicts the rate of subsequent atrophy in patients at early symptomatic Alzheimer disease stages

Tau-PET Signal Predicts Atrophy in Early Alzheimer Disease

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Association between baseline tau-PET and subsequent atrophy particularly strong in younger patients
From 2007 to 2014

2007 to 2014 Saw Decrease in U.S. Incidence of Alzheimer Disease

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Incidence varied considerably by region, ranging from 0 to more than 3 percent across population areas in 2014
Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics

More Hospital Days Seen With Antipsychotic Use in Alzheimer Disease

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Number of hospital days up by more than 50 percent in AD patients initiating antipsychotic medication
More than half of individuals with Down syndrome aged 55 years or older have dementia claims and 32.7 percent have Alzheimer disease claims

Dementia Common in Down Syndrome Patients Aged ≥55

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Dementia incidence 102 cases per 1,000 person-years for individuals aged 55 years or older
Early-stage Alzheimer disease seems to put households at risk for large adverse changes in liquid assets and may reduce net wealth

Early-Stage Alzheimer Disease Has Adverse Financial Consequences

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Robust evidence shows households are at significant risk for large adverse changes in liquid assets
A new drug to treat early Alzheimer disease will be submitted to the U.S. Food and Drug Administration for approval

New Alzheimer Disease Drug to Be Submitted for FDA Approval

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New analysis of study results suggests highest dose of aducanumab may help slow cognitive decline
Long sleep duration predicts seven-year cognitive decline among U.S. Hispanic/Latino patients

Long Sleep Duration Linked to Cognitive Decline in Hispanics

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Long sleep duration predicts seven-year cognitive decline in U.S. Hispanics/Latinos
There seems to be a 20 percent diagnostic error rate with use of non-sex-specific amnestic mild cognitive impairment diagnostic criteria

Sex-Specific Criteria May Up Accuracy for Diagnosis of aMCI

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Non-sex-specific criteria less accurate for diagnosis of amnestic mild cognitive impairment
Exercising may delay brain deterioration in people at high risk for Alzheimer disease

Exercise May Slow Brain Deterioration in Alzheimer Disease

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Findings did not differ between aerobic exercise and stretching and toning