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Tag: Alzheimer’s

A proposed project to map the genes of 1 million people in New York living with or at risk for Alzheimer disease was announced Friday by Gov. Andrew Cuomo.

Alzheimer Disease Gene Mapping Project Proposed in New York State

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Governor says initiative will help researchers working to slow the progression of Alzheimer disease
Two experimental drugs do not appear to slow memory loss or mental decline in patients in the early stages of a rare

Two Experimental Drugs for Rare, Inherited Alzheimer Disease Disappoint

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Both drugs designed to target and neutralize amyloid beta in the brain
Road proximity is associated with an increased incidence of specific neurologic disorders

Road Proximity Linked to Incidence of Neurologic Diseases

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Incidence increased for non-Alzheimer dementia, Parkinson, Alzheimer disease, multiple sclerosis
Suvorexant improves total sleep time in patients with probable Alzheimer disease dementia and insomnia

Suvorexant May Improve Insomnia With Alzheimer Disease

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Suvorexant does not appear to worsen underlying cognitive impairment
No harms come from screening for Alzheimer disease and related dementias in primary care

Primary Care Screening for Dementia Not Harmful

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No increases for depressive, anxiety symptoms seen with screening in rural, suburban, urban primary care clinics
Individuals with Alzheimer disease initiating antipsychotics have an increased risk for head injuries and traumatic brain injury

Antipsychotic Initiation Ups Risk for Head Injury, TBI in Alzheimer Disease

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TBI injury risk up for quetiapine versus risperidone users
The global intensity of the tau-positron emission tomography signal predicts the rate of subsequent atrophy in patients at early symptomatic Alzheimer disease stages

Tau-PET Signal Predicts Atrophy in Early Alzheimer Disease

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Association between baseline tau-PET and subsequent atrophy particularly strong in younger patients
From 2007 to 2014

2007 to 2014 Saw Decrease in U.S. Incidence of Alzheimer Disease

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Incidence varied considerably by region, ranging from 0 to more than 3 percent across population areas in 2014
Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics

More Hospital Days Seen With Antipsychotic Use in Alzheimer Disease

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Number of hospital days up by more than 50 percent in AD patients initiating antipsychotic medication
More than half of individuals with Down syndrome aged 55 years or older have dementia claims and 32.7 percent have Alzheimer disease claims

Dementia Common in Down Syndrome Patients Aged ≥55

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Dementia incidence 102 cases per 1,000 person-years for individuals aged 55 years or older