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Tag: Alzheimer’s

MCI, Dementia Risks Up With Increasing Biological Severity of Alzheimer Disease

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Monotonic increase in lifetime risk of MCI, dementia seen with increasing amyloid PET centiloid value among those who were currently cognitively unimpaired

AI-Driven Method IDs Alzheimer Disease and Related Dementias in Primary Care

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Combining patient-reported questionnaire with AI increased the rate of new diagnoses by 31 percent versus usual care

Neighborhood Deprivation Tied to Poorer Cognition

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Link possibly involves greater burden of small vessel disease and modifiable risk factors

Increased Mortality Seen Among Patients With Early-Onset Dementia

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Frontotemporal dementia spectrum patients have highest all-cause mortality among all dementia subtypes

Intranasal Insulin, Empagliflozin Have Promising Effects on Cognition

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Intranasal insulin increased mPACC-5, modulated fractional anisotropy and cerebral blood flow

Mortality Increased With Benzodiazepines, Antipsychotic Use in ADRD Patients

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Elevated 180-day mortality reported for nursing home residents with Alzheimer disease and related dementias receiving hospice care

FDA Clears New Blood Test to Help Rule Out Alzheimer’s Disease

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The Elecsys pTau181 blood test correctly identified people without Alzheimer’s in 97.9% of cases

Age at Start of Estrogen Therapy May Affect Alzheimer Disease Risk

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Up to 32 percent lower risk conferred by early initiation, while increased risk for dementia seen in studies among older women

PM2.5 Exposure Linked to Increased Dementia Severity

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Higher PM2.5 exposure prior to death linked to increased odds of more severe Alzheimer disease neuropathologic change

Alzheimer Disease Associated With Greater Neural Flexibility

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Neural flexibility also predicts dementia transition