Tag: Alzheimer’s
Social Vulnerability Index Linked to Risk for Alzheimer Disease
Individuals in areas with higher SVI had increased risk for incident AD and faster rate of cognitive decline
Sleep Deficiency Linked to Atrophy of the Inferior Parietal Region of the Brain
Associations seen between less short wave sleep and rapid eye movement sleep with smaller inferior parietal region volumes
Long-Term Gantenerumab May Slow Decline in Dominantly Inherited Alzheimer Disease
Hazard ratio for clinical decline in Clinical Dementia Rating-Sum of Boxes was 0.53 for those treated with gantenerumab the longest
Burden of Alzheimer Disease Rose Worldwide From 1990 to 2021
Additionally, trends show increasing cross-country inequalities, with higher burden in higher sociodemographic index regions
Menopausal Hormone Therapy Linked to Faster Regional Tau Accumulation in Older Women
Hormone therapy has indirect effect on cognitive decline through regional tau accumulation; no links with tau for women younger than 70 years
Prolonged REM Latency Potential Marker for Alzheimer Disease
Highest tertile of REM latency associated with higher Aβ burden, elevated p-tau181, reduced BDNF levels
Certain Drug Types Associated With Risk for Dementia
Antimicrobials, vaccines, anti-inflammatories linked to reduced risk for Alzheimer disease and dementia; antipsychotics and diabetes drugs tied to higher risk
New Criteria Developed for Appropriate Use of Amyloid, Tau PET
17 clinical scenarios developed for which amyloid or tau PET may be considered
Dementia Index Shows Validity for Predicting Age of Onset of MCI, Alzheimer Disease
In simulated trial, FDI achieved mean absolute errors of 1.57 and 0.70 years for predicting MCI, AD onset, respectively
Recommendations Developed for Evaluation of Patients With Alzheimer Disease
Clinical practice guideline also presents recommendations for specialist care and primary care of patients with Alzheimer disease, dementia
