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Tag: Alzheimer’s

Intranasal Insulin, Empagliflozin Have Promising Effects on Cognition

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Intranasal insulin increased mPACC-5, modulated fractional anisotropy and cerebral blood flow

Mortality Increased With Benzodiazepines, Antipsychotic Use in ADRD Patients

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Elevated 180-day mortality reported for nursing home residents with Alzheimer disease and related dementias receiving hospice care

FDA Clears New Blood Test to Help Rule Out Alzheimer’s Disease

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The Elecsys pTau181 blood test correctly identified people without Alzheimer’s in 97.9% of cases

Age at Start of Estrogen Therapy May Affect Alzheimer Disease Risk

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Up to 32 percent lower risk conferred by early initiation, while increased risk for dementia seen in studies among older women

PM2.5 Exposure Linked to Increased Dementia Severity

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Higher PM2.5 exposure prior to death linked to increased odds of more severe Alzheimer disease neuropathologic change

Alzheimer Disease Associated With Greater Neural Flexibility

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Neural flexibility also predicts dementia transition

Sense of Life Purpose Lowers Risk for Cognitive Impairment

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Findings persisted even among people at high genetic risk for dementia

FDA Approves Subcutaneous Leqembi for Treatment of Early Alzheimer Disease

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Leqembi Iqlik allows for at-home maintenance dosing after initial 18 months of intravenous dosing

Mediterranean Diet Beneficial in Those With High Alzheimer Disease Risk

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Adherence to the Mediterranean diet more effectively modulates dementia-related metabolites in APOE4 homozygotes

Lifestyle Interventions Improve Cognition for At-Risk Older Adults

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Significantly greater benefit on global cognition seen for structured versus self-guided intervention over two years