Tag: Alzheimer’s

Both GLP-1 receptor agonists and SGLT2 inhibitors linked to reduced risk for ADRD, with no significant difference between them

Women and those with paternal history of Alzheimer disease have stronger association between Aβ, tau deposition than men or those with maternal history

Statin use linked to reduction in risks for all-cause dementia and Alzheimer disease-related dementia

Individuals in areas with higher SVI had increased risk for incident AD and faster rate of cognitive decline

Associations seen between less short wave sleep and rapid eye movement sleep with smaller inferior parietal region volumes

Hazard ratio for clinical decline in Clinical Dementia Rating-Sum of Boxes was 0.53 for those treated with gantenerumab the longest

Additionally, trends show increasing cross-country inequalities, with higher burden in higher sociodemographic index regions

Hormone therapy has indirect effect on cognitive decline through regional tau accumulation; no links with tau for women younger than 70 years

Highest tertile of REM latency associated with higher Aβ burden, elevated p-tau181, reduced BDNF levels

Antimicrobials, vaccines, anti-inflammatories linked to reduced risk for Alzheimer disease and dementia; antipsychotics and diabetes drugs tied to higher risk