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Adults in their mid-30s to 40s are drinking too much too often

One in Three U.S. Adults Aged 35 to 44 May Have Drinking Problem

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Nine percent continue to drink despite negative effects on career, education, relationships
Women with alcohol-associated cirrhosis are less likely to receive alcohol use disorder treatment than men with the disease even though such treatment is associated with improved outcomes at one year

Gender Gap Seen in Accessing Alcohol Treatment With Cirrhosis

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Women less likely to be treated than men; treatment visit, medication tied to improved one-year outcomes
Assessing the frequency and quantity of alcohol consumption may be inadequate for identifying alcohol-related problems in women who have undergone Roux-en-Y gastric bypass surgery

Alcohol Disorder Screening in Women Post-RYGB Inadequate

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Measuring alcohol intake alone ineffective for identifying alcohol-related problems after Roux-en-Y
There have been substantial increases in complete abstinence from substance use reported by high school students over the past 40 years

Abstinence Rates for Substance Use Increasing Among Teens

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Trends in non-use differed by substance, with marijuana use decreasing the least
Patients with alcoholic cardiomyopathy have more variants in dilated cardiomyopathy-associated genes than those without alcoholic cardiomyopathy

More Variants in DCM-Tied Genes in Alcoholic Cardiomyopathy

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Combination of TTNtv, excess alcohol consumption linked to worse LVEF in dilated cardiomyopathy
Across U.S. counties there is considerable variation in mortality due to alcohol use disorders

Substance Use Mortality Varies Widely Across U.S. Counties

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Considerable variation in mortality due to alcohol and drug use disorders, self-harm, interpersonal violence
Mobile alcohol interventions may help liver transplant candidates with alcoholic liver disease maintain sobriety

Text Message-Based Intervention Helps With Sobriety Maintenance

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Findings among liver transplant candidates with alcoholic liver disease
Alcohol use disorders are associated with increased risk for dementia onset

Alcohol Use Disorders Tied to Increased Risk of Dementia Onset

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Most early-onset dementia cases are alcohol-related or have additional diagnosis of alcohol use disorders
Among married individuals

Alcohol Use Disorder Registration Impacts Risk for Spouse

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Large increase in AUD registration risk in married individuals following first AUD registration in spouse
A newly identified genetic risk variant is associated with comorbid alcohol dependence and major depression in African Americans

Locus ID’d That Links Comorbid Alcohol Dependence, Depression

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Robust association identified for SEMA3A locus in African American participants in two samples