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Use of topical dapsone may have led to the development of methemoglobinemia

Topical Acne Gel Linked to Methemoglobinemia

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Teen developed blood disorder after using Aczone for a week
For patients with preexisting hypertriglyceridemia

Supplements Curb Isotretinoin-Associated Triglyceride Increase

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ω-3 supplementation stabilizes expected increase in patients with preexisting hypertriglyceridemia
There appears to be an association between teenage acne and melanoma

Teenage Acne Linked to Melanoma in Women

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Findings show increased risk of melanoma after adjustment for known risk factors