Lower mortality, adverse cardiac events, bleeding seen across CAD patients
THURSDAY, July 7, 2016 (HealthDay News) — Compared with femoral access for coronary interventions, radial access reduces mortality and major adverse cardiovascular endpoints (MACE) across the spectrum of patients with coronary artery disease (CAD), according to a review published in the June issue of the Journal of the American College of Cardiology: Cardiovascular Interventions.
Giuseppe Ferrante, M.D., Ph.D., from the Humanitas Clinical and Research Center in Italy, and colleagues conducted a systematic literature review to identify randomized trials comparing radial and femoral access for coronary interventions.
The researchers identified 24 studies (22,843 participants). They found that compared with femoral access, radial access was associated with a significantly lower risk of all-cause mortality (odds ratio [OR], 0.71), MACE (OR, 0.84), major bleeding (OR, 0.53), and major vascular complications (OR, 0.23). The two groups had similar rates of myocardial infarction and stroke. Across the whole spectrum of CAD patients, the effects of radial access were consistent.
“These findings support the use of the radial access as the default approach for patients undergoing coronary interventions,” conclude the authors.
Two authors report financial ties to the pharmaceutical industry.
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