Smoking and obesity associated with significantly earlier age of presentation
WEDNESDAY, June 23, 2021 (HealthDay News) — Modifiable risk factors remain widely prevalent among patients undergoing their first percutaneous coronary intervention (PCI), according to a study published online June 9 in PLOS ONE.
Zoya Gurm, from the Wayne State University School of Medicine in Detroit, and colleagues assessed the prevalence of risk factors and their trends among patients without a history of myocardial infarction or revascularization undergoing their first PCI (Jan. 1, 2010, through March 31, 2018). The analysis included 69,571 men and 38,930 women.
The researchers found that 95.5 percent of patients had one or more risk factors and nearly half (55.2 percent of women and 48.7 percent of men) had three or more risk factors. As the number of risk factors increased, the gap between men and women in the mean age at the time of presentation narrowed (gap of six years among those with two risk factors versus less than one year among those with five risk factors). Patients with a current/recent history of smoking presented a decade earlier (56.8 years versus 66.9 years) compared with patients without a current/recent history of smoking. Patients with obesity presented 4.0 years earlier (61.4 years versus 65.4 years) compared with patients without obesity.
“Population-level interventions aimed at preventing obesity and smoking could significantly delay the onset of coronary artery disease and the need for PCI,” the authors write.
Two authors disclosed financial ties to Blue Cross Blue Shield of Michigan.
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