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Excess postoperative mortality and morbidity is seen with use of guideline-based indications for mitral regurgitation surgery versus early surgery

Improved Outcomes With Early Mitral Regurgitation Surgery

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Surgical correction based on high probability of repair linked to improved survival
Among female high school field hockey players

Mandatory Eyewear Cuts Injuries in Girls’ Field Hockey

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National mandate for protective eyewear linked to reduced injuries in girls' high school field hockey
Smoking is a risk factor for clear cell and papillary renal cell carcinoma

Smoking Ups Risk of Some Renal Cell Cancer Histological Subtypes

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Higher risk for clear cell, papillary renal cell carcinoma, but not chromophobe histology
Data relating to the value of bedside physical examinations in the intensive care unit are sparse

Sparse Data Available on Value of Bedside Physical Exams in ICU

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Authors emphasize value of comprehensive physical examination in the ICU despite lack of data
Infection-related hospitalization during childhood is independently associated with adverse adult metabolic variables

Serious Childhood Infection Tied to Metabolic Disease Later in Life

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Early childhood hospitalization for infection tied to increased BMI, metabolic syndrome in adulthood
A drop in carbohydrate antigen 19-9 levels of more than 10 percent after two rounds of chemotherapy is associated with longer survival in patients with advanced pancreatic ductal adenocarcinoma

Antigen Level Signals Response to Chemo for Pancreatic Cancer

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Overall survival, time to progression longer with early drop of >10 percent in carbohydrate antigen 19-9
The diabetes drug metformin changes metabolic profiles of three metabolites that may lower LDL cholesterol

Metabolic Changes With Metformin May Lower LDL-C

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Possible metabolic mechanism includes activation of AMPK, FADS suppression
For patients with a pre-existing unknown nonfunctional kidney

Post-Hysterectomy Cystoscopy May Lead to False-Positive Result

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Incorrect presumption of ureteral injury can occur in patients with a pre-existing nonfunctional kidney
An electronic medical record-based care pathway improves treatment of cellulitis

EMR Care Pathway Aids Treatment of Cellulitis

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Antibiotic use, pharmacy costs, and length of stay cut without affecting readmissions
Limited use of the widely abused painkiller OxyContin in children as young as 11 years old has been approved by the U.S. Food and Drug Administration.

FDA Approves OxyContin for Children As Young As 11

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Duragesic is the only other extended-release opioid with FDA-approved labeling for use in children