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A drop in carbohydrate antigen 19-9 levels of more than 10 percent after two rounds of chemotherapy is associated with longer survival in patients with advanced pancreatic ductal adenocarcinoma

Antigen Level Signals Response to Chemo for Pancreatic Cancer

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Overall survival, time to progression longer with early drop of >10 percent in carbohydrate antigen 19-9
The diabetes drug metformin changes metabolic profiles of three metabolites that may lower LDL cholesterol

Metabolic Changes With Metformin May Lower LDL-C

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Possible metabolic mechanism includes activation of AMPK, FADS suppression
For patients with a pre-existing unknown nonfunctional kidney

Post-Hysterectomy Cystoscopy May Lead to False-Positive Result

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Incorrect presumption of ureteral injury can occur in patients with a pre-existing nonfunctional kidney
An electronic medical record-based care pathway improves treatment of cellulitis

EMR Care Pathway Aids Treatment of Cellulitis

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Antibiotic use, pharmacy costs, and length of stay cut without affecting readmissions
Limited use of the widely abused painkiller OxyContin in children as young as 11 years old has been approved by the U.S. Food and Drug Administration.

FDA Approves OxyContin for Children As Young As 11

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Duragesic is the only other extended-release opioid with FDA-approved labeling for use in children
Large bolt cutters can be used to split titanium rings after multiple failed attempts with other methods

Large Bolt Cutters Can Be Used to Split Titanium Rings in ER

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Pair of large bolt cutters obtained from theatre successfully cut ring after multiple failed attempts
Survivors of childhood cancer have an increased long-term risk of intestinal obstruction requiring surgery

Child CA Survivors Face Risk of Bowel Obstruction Requiring Sx

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Survivors of childhood cancer, especially those with abdominopelvic tumors, have higher long-term risk
During the 2009 to 2010 pandemic flu season

Pregnancy Mortality Due to H1N1 ’09 to ’10 Pandemic: 12 Percent

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Findings based on confirmed and possible influenza A deaths in the United States
High levels of job stress may increase the risk of sick leave due to mental health disorders

Physical Activity Reduces Risk of Mental Health Sick Leave

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Those with high job strain, little social support, unhealthy lifestyles at greater risk for sick leave
Concerns that eye injections of the drug bevacizumab increase the risk of endophthalmitis may be unfounded

Study: No Higher Eye Infection Risk With Bevacizumab

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Rates of endophthalmitis were 0.017 percent for bevacizumab and 0.025 percent for ranibizumab